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Bouton, Tara C. ; Phillips, Patrick P. J. ; Mitnick, Carole D. ; Peloquin, Charles A. ; Eisenach, Kathleen ; Patientia, Ramonde F. ; Lecca, Leonid ; Gotuzzo, Eduardo ; Gandhi, Neel R. ; Butler, Donna ; Diacon, Andreas H. ; Martel, Bruno ; Santillan, Juan ; Hunt, Kathleen Robergeau ; Vargas, Dante ; von Groote-Bidlingmaier, Florian ; Seas, Carlos ; Dianis, Nancy ; Moreno-Martinez, Antonio ; Horsburgh, C. Robert | BMC | 2019-01-25T16:59:36ZBACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroqu[...]texto impreso
Lam, Edward P. ; Moore, Cecilia L. ; Gotuzzo, Eduardo ; Nwizu, Chidi ; Kamarulzaman, Adeeba ; Chetchotisakd, Ploenchan ; van Wyk, Jean ; Teppler, Hedy ; Kumarasamy, Nagalingeswaran ; Molina, Jean-Michel ; Emery, Sean ; Cooper, David A. ; Boyd, Mark A. ; SECOND-LINE Study Group | Mary Ann Liebert | 2019-02-22T14:54:32ZWe investigate mutations and correlates according to HIV-1 subtype after virological failure (VF) of standard first-line antiretroviral therapy (ART) (non-nucleoside/nucleotide reverse transcriptase inhibitor [NNRTI] +2 nucleoside/nucleotide rev[...]texto impreso
Vilchez, Gustavo ; Espinoza, Miguel ; D'Onadio, Guery ; Saona, Pedro ; Gotuzzo, Eduardo | Elsevier | 2019-02-06T14:52:37ZOBJECTIVE: Brucellosis is a zoonosis with high morbidity in humans. This disease has gained interest recently due to its re-emergence and potential for weaponization. Pregnant women with this disease can develop severe complications. Its associ[...]texto impreso
Neumayr, Andreas ; Ollague, Jose ; Bravo, Francisco ; Gotuzzo, Eduardo ; Jiménez, Pedro ; Norton, Scott-A. ; Doanh, Pham-Ngoc ; Nawa, Yukifumi ; Horii, Yoichiro ; Nickel, Beatrice ; Marti, Hanspeter | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:45:56ZGnathostomiasis is a zoonotic parasitosis endemic in many Asian and some Latin American countries. Most human infections are caused by Gnathostoma spinigerum in Asia and Gnathostoma binucleatum in the Americas, and recently, imported cases have [...]texto impreso
Franco-Paredes, Carlos ; Marcos, Luis A. ; Henao-Martínez, Andrés F. ; Rodriguez-Morales, Alfonso J. ; Villamil-Gómez, Wilmer E. ; Gotuzzo, Eduardo ; Bonifaz, Alexandro | American Society for Microbiology | 2019-01-25T17:02:40ZHumans encounter mycobacterial species due to their ubiquity in different environmental niches. In many individuals, pathogenic mycobacterial species may breach our first-line barrier defenses of the innate immune system and modulate the activat[...]texto impreso
Wolff, Marcelo J. ; Giganti, Mark J. ; Cortes, Claudia P. ; Cahn, Pedro ; Grinsztejn, Beatriz ; Pape, Jean W. ; Padgett, Denis ; Sierra-Madero, Juan ; Gotuzzo, Eduardo ; Duda, Stephany N. ; McGowan, Catherine C. ; Shepherd, Bryan E. ; CCASAnet | Public Library of Science | 2019-01-25T15:02:13ZBACKGROUND: In Latin America, the first wave of HIV-infected patients initiated highly active antiretroviral therapy (HAART) 10 or more years ago. Characterizing their treatment experience and corresponding outcomes across a decade of HAART may [...]texto impreso
Felgner, Jiin ; Jain, Aarti ; Nakajima, Rie ; Liang, Li ; Jasinskas, Algis ; Gotuzzo, Eduardo ; Vinetz, Joseph M. ; Miyajima, Fabio ; Pirmohamed, Munir ; Hassan-Hanga, Fatimah ; Umoru, Dominic ; Jibir, Binta Wudil ; Gambo, Safiya ; Olateju, Kudirat ; Felgner, Philip L. ; Obaro, Stephen ; Davies, D. Huw | Public Library of Science | 2019-01-25T15:18:33ZImproved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella ent[...]texto impreso
Caro-Vega, Yanink ; Belaunzaran-Zamudio, Pablo F. ; Crabtree-Ramirez, Brenda E. ; Shepherd, Bryan E. ; Grinsztejn, Beatriz ; Wolff, Marcelo ; Pape, Jean W. ; Padgett, Denis ; Gotuzzo, Eduardo ; McGowan, Catherine C. ; Sierra-Madero, Juan G. | Oxford University Press | 2018-06-18T15:26:48ZBackground Efavirenz (EFV) and boosted protease inhibitors (bPIs) are still the preferred options for firstline antiretroviral regimens (firstline ART) in Latin America and have comparable short-term efficacy. We assessed the long-term durabilit[...]texto impreso
Franco-Paredes, Carlos ; Khan, M. Imran ; Gonzalez-Diaz, Esteban ; Santos-Preciado, Jose-I. ; Rodriguez-Morales, Alfonso-J. ; Gotuzzo, Eduardo | Public Library of Science | 2019-02-06T14:51:19Ztexto impreso
Malpica, Luis ; Pimentel, Agustin ; Reis, Isildinha M. ; Gotuzzo, Eduardo ; Lekakis, Lazaros ; Komanduri, Krishna ; Harrington, Thomas ; Barber, Glen N. ; Ramos, Juan C. | The American Society of Hematology | 2018-08-10T20:11:15ZAdult T-cell leukemia/lymphoma (ATLL) is a fatal disease caused by human T-cell leukemia virus type 1 (HTLV-1). We retrospectively analyzed 195 patients with ATLL (lymphomatous n = 96, acute n = 80, unfavorable chronic n = 7, chronic n = 5, smol[...]texto impreso
Alvarez, Carolina ; Gotuzzo, Eduardo ; Vandamme, Anne-Mieke ; Verdonck, Kristien | Frontiers Media | 2019-02-22T14:56:08ZHuman T-lymphotropic virus 1 (HTLV-1) is a retrovirus that produces a persistent infection. Two transmission routes (from mother to child and via sexual intercourse) favor familial clustering of HTLV-1. It is yet unknown why most HTLV-1 carriers[...]texto impreso
Menezes, Soraya Maria ; Leal, Fabio E. ; Dierckx, Tim ; Khouri, Ricardo ; Decanine, Daniele ; Silva-Santos, Gilvaneia ; Schnitman, Saul V. ; Kruschewsky, Ramon ; Lopez, Giovanni ; Alvarez, Carolina ; Talledo, Michael ; Gotuzzo, Eduardo ; Nixon, Douglas F. ; Vercauteren, Jurgen ; Brassat, David ; Liblau, Roland ; Vandamme, Anne Mieke ; Galvao-Castro, Bernardo ; Van Weyenbergh, Johan | Frontiers Media | 2019-01-25T15:02:14ZHuman T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals develops either ATL or [...]texto impreso
Nabeta, Pamela ; Havumaki, Joshua ; Ha, Dang Thi Minh ; Cáceres, Tatiana ; Hang, Pham Thu ; Collantes, Jimena ; Thi Ngoc Lan, Nguyen ; Gotuzzo, Eduardo ; Denkinger, Claudia M. | Public Library of Science | 2019-01-25T15:18:35ZBACKGROUND: Improved and affordable diagnostic or triage tests are urgently needed at the microscopy centre level. Automated digital microscopy has the potential to overcome issues related to conventional microscopy, including training time requ[...]texto impreso
Cabello-Vílchez, Alfonso Martín ; Martin-Navarro, Carmen Maria ; Lopez-Arencibia, Atteneri ; Reyes-Batlle, Maria ; Gonzalez, Ana C. ; Guerra, Humberto ; Gotuzzo, Eduardo ; Valladares, Basilio ; Pinero, Jose E. ; Lorenzo-Morales, Jacob | Elsevier | 2020-06-10T18:11:37ZFree Living Amoebae (FLA) of Acanthamoeba genus are widely distributed in the environment and can be found in the air, soil and water; and have also been isolated from air-conditioning units. In humans, they are causative agents of a sight-threa[...]texto impreso
Zavaleta, Carol ; Konda, Kelika ; Valderrama, Yadira ; Gotuzzo, Eduardo | Springer | 2019-02-22T14:55:50Z
