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Miranda, J. Jaime ; Moscoso, Miguel G. ; Yan, Lijing L. ; Diez-Canseco, Francisco ; Malaga, German ; Garcia, Hector H. ; Ovbiagele, Bruce | Elsevier | 2019-01-25T16:59:36ZStroke is a major cause of death and disability, with most of its burden now affecting low- and middle-income countries (LMIC). People in rural areas of LMIC who have a stroke receive very little acute stroke care and local healthcare workers an[...]texto impreso
Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-07-04T16:59:18ZBackground: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable amon[...]texto impreso
Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-12-06T21:02:55ZBACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypo[...]texto impreso
Arroyo, Gianfranco ; Rodriguez, Silvia ; Lescano, Andres G. ; Alroy, Karen A. ; Bustos, Javier A. ; Santivañez, Saul ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2018-11-30T02:09:29ZBackground: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervo[...]texto impreso
Antiparasitic agents against Taenia solium cysticercosis have been in use since 1979, although its use has been questioned on the basis that cysts would die naturally and thus treatment-induced inflammation is unnecessary. In addition, isolated [...]texto impreso
Garcia, Hector H. ; Gonzalez, Armando E. ; O'Neal, Seth E. ; Gilman, Robert H. | Instituto Nacional de Salud | 2018-11-30T22:50:34ZNeurocysticercosis is the infection of the nervous system by the larvae (cysticerci) of the pork tapeworm Taenia solium. Neurocysticercosis is the major cause of acquired epilepsy worldwide and as such, it represents a global health problem. On [...]texto impreso
Flecker, Robert H. ; Pray, Ian W. ; Santivanez, Saul J. ; Ayvar, Viterbo ; Gamboa, Ricardo ; Muro, Claudio ; Moyano, Luz Maria ; Benavides, Victor ; Garcia, Hector H. ; O'Neal, Seth E. | Public Library of Science | 2019-01-25T15:02:18ZBACKGROUND: Taenia solium inflicts substantial neurologic disease and economic losses on rural communities in many developing nations. "Ring-strategy" is a control intervention that targets treatment of humans and pigs among clusters of househol[...]texto impreso
Mejia Maza, Alan J. ; Carmen-Orozco, Rogger P. ; Carter, Emma ; Dávila, Danitza G. ; Castillo, Gino ; Morales, Jemina D. ; Mamani, Javier ; Gavidia, Cesar ; Alroy, Joseph ; Sterling, Charles R. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Woltjer, Randy L. ; Verastegui, Manuela R. ; Gilman, Robert H. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T02:09:30ZNeurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of the Taenia solium and is the leading cause of preventable epilepsy world-wide. However, the pathophysiology and relation to the wide range of c[...]texto impreso
Beam, Michelle ; Spencer, Angela ; Fernandez, Lauralee ; Atto, Ruth ; Muro, Claudio ; Vilchez, Percy ; Gamboa, Ricardo ; Olaya, Sandra ; Ayvar, Viterbo ; Gonzalez, Armando E. ; Garcia, Hector H. ; O'Neal, Seth E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T02:09:30ZInfection of the brain with Taenia solium larvae (neurocysticercosis) is a leading cause of preventable epilepsy worldwide. Effective and sustainable strategies to control parasite transmission in rural endemic communities are needed to prevent [...]texto impreso
Carmen-Orozco, Rogger P. ; Dávila-Villacorta, Danitza G. ; Cauna, Yudith ; Bernal-Teran, Edson G. ; Bitterfeld, Leandra ; Sutherland, Graham L. ; Chile, Nancy ; Céliz, Rensson H. ; Ferrufino-Schmidt, Maria C. ; Gavidia, Cesar M. ; Sterling, Charles R. ; Garcia, Hector H. ; Gilman, Robert H. ; Verástegui, Manuela Renee | Wiley | 2018-11-30T02:09:30ZNeurocysticercosis (NCC) is a helminth infection affecting the central nervous system caused by the larval stage (cysticercus) of Taenia solium. Since vascular alteration and blood-brain barrier (BBB) disruption contribute to NCC pathology, it i[...]texto impreso
Miranda, J. Jaime ; Bernabé-Ortiz, Antonio ; Diez-Canseco, Francisco ; Malaga, German ; Cárdenas, María K. ; Carrillo-Larco, Rodrigo M. ; Pesantes, M. Amalia ; Araya, Ricardo ; Boggio, Oscar ; Checkley, William ; García, Patricia J. ; Leon-Velarde, Fabiola ; Lescano, Andres G. ; Montori, Victor ; Pan, William ; Rivera-Chira, Maria ; Sacksteder, Katherine ; Smeeth, Liam ; Garcia, Hector H. ; Gilman, Robert H. | Elsevier | 2019-02-06T14:59:06ZThe CRONICAS Centre of Excellence in Chronic Diseases, based at Universidad Peruana Cayetano Heredia, was created in 2009 with support from the U.S. National Heart, Lung, and Blood Institute (NHLBI). The vision of CRONICAS is to build a globally[...]texto impreso
Del Brutto, Oscar H. ; Salgado, Perla ; Lama, Julio ; Del Brutto, Victor J. ; Campos, Xavier ; Zambrano, Mauricio ; Garcia, Hector H. | American Society of Tropical Medicine and Hygiene | 2020-06-10T18:11:34ZCalcified neurocysticercosis has been associated with hippocampal atrophy in patients with refractory epilepsy, but the relevance of this association in the population at large is unknown. We assessed calcified cysticerci and its association wit[...]texto impreso
Del Brutto, Oscar H. ; Salgado, Perla ; Lama, Julio ; Del Brutto, Victor J. ; Campos, Xavier ; Zambrano, Mauricio ; Garcia, Hector H. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:57:39ZCalcified neurocysticercosis has been associated with hippocampal atrophy in patients with refractory epilepsy, but the relevance of this association in the population at large is unknown. We assessed calcified cysticerci and its association wit[...]texto impreso
Alroy, Karen A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Gonzales-Gustavson, Eloy ; Gallegos, Linda ; Gavidia, Cesar M. ; Verastegui, Manuela ; Rodriguez, Silvia ; López, Teresa ; Gomez-Puerta, Luis A. ; Alroy, Joseph ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T02:09:30ZNeurocysticercosis (NCC), the infection of the human central nervous system (CNS) with larval cysts of Taenia solium causes widespread neurological morbidity. Animal models are crucial for studying the pathophysiology and treatment of NCC. Some [...]texto impreso
León-Janampa, Nancy ; Liendo, Ruddy ; Gilman, Robert H. ; Padilla, Carlos ; Garcia, Hector H. ; Gonzales, Armando ; Sheen, Patricia ; Pajuelo, Monica J. ; Zimic, Mirko ; Cysticercosis Working Group in Peru | Elsevier | 2019-07-04T16:59:24ZPorcine cysticercosis is an endemic parasitic disease caused by infection with Taenia solium that is found predominantly in developing countries. In order to aid in the development of simple diagnostic approaches, identification and characteriza[...]
