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Araujo, Maisa da Silva ; Andrade, Alice Oliveira ; Santos, Najara Akira Costa Dos ; Pereira, Dhelio Batista ; Costa, Glaucilene da Silva ; Paulo, Paula Frassinetti Medeiros de ; Rios, Carlos Tong ; Moreno, Marta ; Pereira-da-Silva, Luiz Hidelbrando ; Medeiros, Jansen Fernandes de | Sociedade Brasileira de Medicina Tropical | 2019-12-06T21:02:51ZINTRODUCTION: The lack of highly-productive Nyssorhynchus darlingi laboratory colonies limits some studies. We report the first well-established laboratory colony of Ny. darlingi in Brazil. METHODS: Mosquitoes were collected from Porto Velho and[...]texto impreso
Araujo, Maisa da Silva ; Andrade, Alice Oliveira ; Costa dos Santos, Najara Akira ; Pereira, Dheprimelio Batista ; Costa, Glaucilene da Silva ; Medeiros de Paulo, Paula Frassinetti ; Tong Rios, Carlos ; Moreno, Marta ; Pereira-da-Silva, Luiz Hidelbrando ; de Medeiros, Jansen Fernandes | Sociedade Brasileira de Medicina Tropical | 2019-08-08T15:23:48ZINTRODUCTION: The lack of highly-productive Nyssorhynchus darlingi laboratory colonies limits some studies. We report the first well-established laboratory colony of Ny. darlingi in Brazil. METHODS: Mosquitoes were collected from Porto Velho and[...]texto impreso
Lainhart, William ; Bickersmith, Sara A. ; Moreno, Marta ; Rios, Carlos Tong ; Vinetz, Joseph M. ; Conn, Jan E. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:57:38ZThe process of colonizing any arthropod species, including vector mosquitoes, necessarily involves adaptation to laboratory conditions. The adaptation and evolution of colonized mosquito populations needs consideration when such colonies are use[...]texto impreso
Moreno, Marta ; Tong-Rios, Carlos ; Orjuela-Sanchez, Pamela ; Carrasco-Escobar, Gabriel ; Campo, Brice ; Gamboa, Dionicia ; Winzeler, Elizabeth A. ; Vinetz, Joseph M. | American Chemical Society | 2018-11-30T02:09:31ZIn vitro culture of Plasmodium vivax liver stages underlies key understandings of the fundamental biology of this parasite, particularly the latent, hyponozoite stage, toward drug and vaccine development. Here, we report systematic production of[...]texto impreso
Orjuela-Sanchez, Pamela ; Villa, Zaira Hellen ; Moreno, Marta ; Tong-Rios, Carlos ; Meister, Stephan ; LaMonte, Gregory M. ; Campo, Brice ; Vinetz, Joseph M. ; Winzeler, Elizabeth A. | American Chemical Society | 2018-11-30T03:10:44ZTo develop new drugs and vaccines for malaria elimination, it will be necessary to discover biological interventions, including small molecules that act against Plasmodium vivax exoerythrocytic forms. However, a robust in vitro culture system fo[...]texto impreso
LaMonte, Gregory M. ; Orjuela-Sanchez, Pamela ; Calla, Jaeson ; Wang, Lawrence T. ; Li, Shangzhong ; Swann, Justine ; Cowell, Annie N. ; Zou, Bing Yu ; Abdel-Haleem Mohamed, Alyaa M. ; Villa Galarce, Zaira Hellen ; Moreno, Marta ; Tong Rios, Carlos ; Vinetz, Joseph M. ; Lewis, Nathan ; Winzeler, Elizabeth A. | Nature Research | 2019-07-04T16:59:30ZThe exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal immunity gene, mucin[...]texto impreso
Rosas-Aguirre, Angel ; Gamboa, Dionicia ; Manrique, Paulo ; Conn, Jan-E. ; Moreno, Marta ; Lescano, Andres-G. ; Sanchez, Juan-F. ; Rodriguez, Hugo ; Silva, Hermann ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph-M. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:45:58ZMalaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The 1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the Amazon region, including areas near to Iquitos, the capital city, but sporad[...]texto impreso
Lainhart, William ; Bickersmith, Sara A. ; Nadler, Kyle J. ; Moreno, Marta ; Saavedra, Marlon P. ; Chu, Virginia M. ; Ribolla, Paulo E. ; Vinetz, Joseph M. ; Conn, Jan E. | BMC | 2019-02-06T14:53:06ZBACKGROUND: The major Neotropical malaria vector, Anopheles darlingi, was reintroduced into the Iquitos, Loreto, Peru area during the early 1990s, where it displaced other anophelines and caused a major malaria epidemic. Since then, case numbers[...]texto impreso
Carrasco-Escobar, Gabriel ; Manrique, Edgar ; Ruiz-Cabrejos, Jorge ; Saavedra, Marlon ; Alava, Freddy ; Bickersmith, Sara ; Prussing, Catharine ; Vinetz, Joseph M. ; Conn, Jan E. ; Moreno, Marta ; Gamboa, Dionicia | Public Library of Science | 2019-07-04T17:00:15ZInterest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective aga[...]texto impreso
Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-12-06T20:57:48ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]texto impreso
Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-08-08T15:23:47ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]texto impreso
Moreno, Marta ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Lainhart, William ; Tong, Carlos ; Alava, Freddy ; Vinetz, Joseph M. ; Conn, Jan E. | BMC | 2019-02-06T14:53:06ZBACKGROUND: Malaria transmission in the peri-Iquitos region of Amazonian Peru has been designated as seasonal and hypo-endemic with recently described hyper-endemic hotspots. Despite relatively recent distribution of long-lasting insecticidal be[...]texto impreso
Moreno, Marta ; Tong, Carlos ; Guzman, Mitchel ; Chuquiyauri, Raúl ; Llanos-Cuentas, Alejandro ; Rodriguez, Hugo ; Gamboa, Dionicia ; Meister, Stephan ; Winzeler, Elizabeth A. ; Maguina, Paula ; Conn, Jan E. ; Vinetz, Joseph M. | American Society of Tropical Medicine and Hygiene | 2020-06-10T18:11:37ZAnopheles darlingi Root is the most important malaria vector in the Amazonia region of South America. However, continuous propagation of An. darlingi in the laboratory has been elusive, limiting entomological, genetic/genomic, and vector-pathoge[...]texto impreso
Quinones, Martha L. ; Norris, Douglas E. ; Conn, Jan E. ; Moreno, Marta ; Burkot, Thomas R. ; Bugoro, Hugo ; Keven, John B. ; Cooper, Robert ; Yan, Guiyun ; Rosas, Angel ; Palomino, Miriam ; Donnelly, Martin J. ; Mawejje, Henry D. ; Eapen, Alex ; Montgomery, Jacqui ; Coulibaly, Mamadou B. ; Beier, John C. ; Kumar, Ashwani | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:57:38ZScale-up of the main vector control interventions, residual insecticides sprayed on walls or structures and/or impregnated in bed nets, together with prompt diagnosis and effective treatment, have led to a global reduction in malaria transmissi[...]texto impreso
Moreno, Marta ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Prussing, Catharine ; Michalski, Adrian ; Tong Rios, Carlos ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-01-25T15:28:04ZAnopheles darlingi, the main malaria vector in the Neotropics, has been considered to be highly anthropophilic. However, many behavioral aspects of this species remain unknown, such as the range of blood-meal sources. Barrier screens were used t[...]
