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Schwalb, A. ; Cachay, R. ; de la Flor, A. ; García, C. ; Seas, C. | Elsevier B.V. | 2020-12-14T16:10:11ZBackground: Despite high mortality rates, physicians can alter the course of the Staphylococcus aureus bacteraemia (SAB) by following recommended standards of care. We aim to assess the adherence of these guidelines and their impact on mortality[...]texto impreso
Shah, L. ; Rojas, M. ; Mori, O. ; Zamudio, C. ; Kaufman, J. S. ; Otero, L. ; Gotuzzo, E. ; Seas, C. ; Brewer, T. F. | Cambridge University Press | 2019-01-25T15:02:22ZWe compared the cost-effectiveness (CE) of an active case-finding (ACF) programme for household contacts of tuberculosis (TB) cases enrolled in first-line treatment to routine passive case-finding (PCF) within an established national TB programm[...]texto impreso
Shah, L. ; Choi, H. W. ; Berrang-Ford, L. ; Henostroza, G. ; Krapp, F. ; Zamudio, C. ; Heymann, S. J. ; Kaufman, J. S. ; Ciampi, A. ; Seas, C. ; Gotuzzo, E. ; Brewer, T. F. | International Union Against Tuberculosis and Lung Disease | 2020-06-10T18:11:30ZSETTING: Peru reports among the highest multidrug-resistant tuberculosis (MDR-TB) rates in the Americas, with a growing proportion in previously untreated tuberculosis (TB) cases. The identification of clusters of primary MDR-TB compared with dr[...]texto impreso
Quispe, R. ; Valle, G. A. ; Huapaya, J. A. ; Novoa, I. ; Giraldo, J. ; Cáceres, T. ; Gotuzzo, E. ; Zamudio, C. ; Seas, C. | International Union Against Tuberculosis and Lung Disease | 2019-02-06T14:45:58ZOBJECTIVE: To evaluate the diagnostic performance of manual MGIT (MMGIT) compared to the gold standard, Lowenstein-Jensen (LJ), in the diagnosis of pulmonary tuberculosis (TB) in a high-burden setting. METHODS: Individuals with suspected TB enro[...]texto impreso
Sudbury, E.L. ; Otero, L. ; Tebruegge, M. ; Messina, N.L. ; Seas, C. ; Montes, M. ; Rìos, J. ; Germano, S. ; Gardiner, K. ; Clifford, V. ; Gotuzzo, E. ; Curtis, N. | Elsevier | 2019-07-04T17:00:19ZThe tuberculin skin test and interferon-gamma release assays have limitations in diagnosing tuberculosis (TB), particularly in children. This study investigated the performance of candidate M. tuberculosis-specific cytokine biomarkers for TB in [...]texto impreso
Shah, L. ; Rojas Peña, M. ; Mori, O. ; Zamudio, C. ; Kaufman, J.S. ; Otero, L. ; Gotuzzo, E. ; Seas, C. ; Brewer, T.F. | Elsevier B.V. | 2020-12-14T16:10:13ZBackground: Active case finding (ACF) in household contacts of tuberculosis (TB) patients is now recommended for National TB Programs (NTP) in low- and middle-income countries. However, evidence supporting these recommendations remains limited. [...]texto impreso
Barletta, F. ; Otero, L. ; de Jong, B.C. ; Iwamoto, T. ; Arikawa, K. ; Van der Stuyft, P. ; Niemann, S. ; Merker, M. ; Uwizeye, C. ; Seas, C. ; Rigouts, L. | American Society for Microbiology | 2019-04-24T18:23:53ZSputum samples from new tuberculosis (TB) cases were collected over 2 years as part of a prospective study in the northeastern part of Lima, Peru. To measure the contribution of recent transmission to the high rates of multidrug resistance (MDR)[...]texto impreso
Sedamano, J. ; Schwalb, A. ; Cachay, R. ; Zamudio, C. ; Ugarte-Gil, C. ; Soto-Cabezas, G. ; Munayco, C.V. ; Seas, C. | BioMed Central Ltd. | 2020-12-14T16:10:12ZBackground: Tuberculosis (TB) transmission has long been recognized as an important occupational hazard for healthcare workers (HCWs). HCWs have a 5.8% annual risk of exposure and three times greater risk of developing active TB than the general[...]texto impreso
Barletta, F. ; Zamudio, C. ; Rigouts, L. ; Seas, C. | Instituto Nacional de Salud | 2020-06-10T18:12:21ZObjetivos. Determinar los perfiles de resistencia de las quinolonas; ciprofloxacina (Cpx), ofloxacina (Ofx), gatifloxacina (Gfx) y moxifloxacina (Mfx), y de los inyectables; kanamicina (Km), amikacina (Am) y capreomicina (Cm) en cepas multidrogo[...]texto impreso
Seas, C. ; García, Coralith ; Salles, M. J. ; Labarca, J. ; Luna, C. ; Alvarez-Moreno, C. ; Mejía-Villatoro, C. ; Zurita, J. ; Guzmán-Blanco, M. ; Rodríguez-Noriega, E. ; Reyes, J. ; Arias, C. A. ; Carcamo, C. ; Gotuzzo, E. | Oxford University Press | 2018-03-22T23:38:48Z"Substantial heterogeneity in the epidemiology and management of Staphylococcus aureus bacteraemia (SAB) occurs in Latin America. We conducted a prospective cohort study in 24 hospitals from nine Latin American countries. To assess the clinical [...]texto impreso
Otero, L. ; De Orbegoso, A. ; Navarro, A. F. ; Rìos, J. ; Parraga, T. ; Gotuzzo, E. ; Seas, C. ; Van der Stuyft, P. | Wiley | 2019-02-06T14:57:42ZOBJECTIVE: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. METHODS: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it bet[...]
