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Saunders, Matthew J. ; Tovar, Marco A. ; Collier, Dami ; Baldwin, Matthew R. ; Montoya, Rosario ; Valencia, Teresa R. ; Gilman, Robert H. ; Evans, Carlton A. | Elsevier | 2019-07-04T16:59:18ZBACKGROUND: Active case-finding among contacts of patients with tuberculosis is a global health priority, but the effects of active versus passive case-finding are poorly characterised. We assessed the contribution of active versus passive case-[...]texto impreso
Wingfield, Tom ; Tovar, Marco A. ; Datta, Sumona ; Saunders, Matthew J. ; Evans, Carlton A. | Elsevier | 2018-12-03T17:04:42Ztexto impreso
Heitzinger, Kristen ; Hawes, Stephen E. ; Rocha, Claudio A. ; Álvarez, Carlos ; Evans, Carlton A. | American Society of Tropical Medicine and Hygiene | 2020-07-14T00:01:15ZApproximately two billion people lack access to microbiologically safe drinking water globally. Boiling is the most popular household water treatment method and significantly reduces diarrheal disease, but is often practiced inconsistently or in[...]texto impreso
Datta, Sumona ; Sherman, Jonathan M. ; Bravard, Marjory A. ; Valencia, Teresa ; Gilman, Robert H. ; Evans, Carlton A. | Oxford University Press | 2019-02-06T14:52:17ZBACKGROUND: It is difficult to determine whether early tuberculosis treatment is effective in reducing the infectiousness of patients' sputum, because culture takes weeks and conventional acid-fast sputum microscopy and molecular tests cannot d[...]texto impreso
Datta, Sumona ; Shah, Lena ; Gilman, Robert H. ; Evans, Carlton A. | Elsevier | 2019-01-25T15:02:20ZBACKGROUND: The performance of laboratory tests to diagnose pulmonary tuberculosis is dependent on the quality of the sputum sample tested. The relative merits of sputum collection methods to improve tuberculosis diagnosis are poorly characteris[...]texto impreso
Rudgard, William E. ; Evans, Carlton A. ; Sweeney, Sedona ; Wingfield, Tom ; Lonnroth, Knut ; Barreira, Draurio ; Boccia, Delia | Public Library of Science | 2019-01-25T15:02:21ZBACKGROUND: Illness-related costs for patients with tuberculosis (TB) ?20% of pre-illness annual household income predict adverse treatment outcomes and have been termed "catastrophic." Social protection initiatives, including cash transfers, ar[...]texto impreso
Oberhelman, Richard A. ; Soto-Castellares, Giselle ; Gilman, Robert H. ; Castillo, Maria E. ; Kolevic, Lenka ; Delpino, Trinidad ; Saito, Mayuko ; Salazar-Lindo, Eduardo ; Negron, Eduardo ; Montenegro, Sonia ; Laguna-Torres, V. Alberto ; Maurtua-Neumann, Paola ; Datta, Sumona ; Evans, Carlton A. | Public Library of Science | 2019-02-06T14:53:11ZBACKGROUND: Diagnosing tuberculosis in children is challenging because specimens are difficult to obtain and contain low tuberculosis concentrations, especially with HIV-coinfection. Few studies included well-controls so test specificities are [...]texto impreso
Lee, Gwenyth O. ; Comina, Germán ; Hernández-Córdova, Gustavo ; Naik, Nehal ; Gayoso, Oscar ; Ticona, Eduardo ; Coronel, Jorge ; Evans, Carlton A. ; Zimic, Mirko ; Paz-Soldan, Valerie A. ; Gilman, Robert H. ; Oberhelman, Richard | Public Library of Science | 2020-07-14T00:02:31ZCough is a characteristic symptom of tuberculosis, is the main cause of transmission, and is used to assess treatment response. We aimed to identify the best measure of cough severity and characterize changes during initial tuberculosis therapy.[...]texto impreso
Proaño, Alvaro ; Bui, David P. ; López, José W. ; Vu, Nancy M. ; Bravard, Marjory A. ; Lee, Gwenyth O. ; Tracey, Brian H. ; Xu, Ziyue ; Comina, Germán ; Ticona, Eduardo ; Mollura, Daniel J. ; Friedland, Jon S. ; Moore, David A. J. ; Evans, Carlton A. ; Caligiuri, Philip ; Gilman, Robert H. | Elsevier | 2018-11-30T03:10:43ZBACKGROUND: Cough frequency, and its duration, is a biomarker that can be used in low-resource settings without the need of laboratory culture and has been associated with transmission and treatment response. Radiologic characteristics associate[...]texto impreso
Wingfield, Tom ; Boccia, Delia ; Tovar, Marco ; Gavino, Arquimedes ; Zevallos, Karine ; Montoya, Rosario ; Lonnroth, Knut ; Evans, Carlton A. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: Even when tuberculosis (TB) treatment is free, hidden costs incurred by patients and their households (TB-affected households) may worsen poverty and health. Extreme TB-associated costs have been termed "catastrophic" but are poorl[...]texto impreso
Wingfield, Tom ; Boccia, Delia ; Tovar, Marco A. ; Huff, Doug ; Montoya, Rosario ; Lewis, James J. ; Gilman, Robert H. ; Evans, Carlton A. | BMC | 2019-02-06T14:52:15ZBackground. Cash transfers are key interventions in the World Health Organisation’s post-2015 global TB policy. However, evidence guiding TB-specific cash transfer implementation is limited. We designed, implemented and refined a novel TB-specif[...]texto impreso
Dudley, Matthew Z. ; Sheen, Patricia ; Gilman, Robert H. ; Ticona, Eduardo ; Friedland, Jon S. ; Kirwan, Daniela E. ; Caviedes, Luz ; Rodriguez, Richard ; Cabrera, Lilia Z. ; Coronel, Jorge ; Grandjean, Louis ; Moore, David A. J. ; Evans, Carlton A. ; Huaroto, Luz ; Chavez-Perez, Victor ; Zimic, Mirko | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:45:12ZHospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB. Pyrazinamide (PZA[...]texto impreso
Proaño, Alvaro ; Bravard, Marjory A. ; López, José W. ; Lee, Gwenyth O. ; Bui, David ; Datta, Sumona ; Comina, Germán ; Zimic, Mirko ; Coronel, Jorge ; Caviedes, Luz ; Cabrera, Jose L. ; Salas, Antonio ; Ticona, Eduardo ; Vu, Nancy M. ; Kirwan, Daniela E. ; Loader, Maria-Cristina I. ; Friedland, Jon S. ; Moore, David A. J. ; Evans, Carlton A. ; Tracey, Brian H. ; Gilman, Robert H. | Oxford University Press | 2019-01-25T16:59:37ZBackground: Cough is the major determinant of tuberculosis transmission. Despite this, there is a paucity of information regarding characteristics of cough frequency throughout the day and in response to tuberculosis therapy. Here we evaluate th[...]texto impreso
Metcalf, Tatiana ; Soria, Jaime ; Montano, Silvia M. ; Ticona, Eduardo ; Evans, Carlton A. ; Huaroto, Luz ; Kasper, Matthew ; Ramos, Eric S. ; Mori, Nicanor ; Jittamala, Podjanee ; Chotivanich, Kesinee ; Chavez, Irwin F. ; Singhasivanon, Pratap ; Pukrittayakamee, Sasithon ; Zunt, Joseph R. | Public Library of Science | 2018-11-30T03:10:46ZBACKGROUND: Meningitis caused by Mycobacterium tuberculosis is a major cause of morbidity and mortality worldwide. We evaluated the performance of cerebrospinal fluid (CSF) testing with the GeneXpert MTB/RIF assay versus traditional approaches f[...]texto impreso
