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Correa, Malena ; Zimic, Mirko ; Barrientos, Franklin ; Barrientos, Ronald ; Roman-Gonzalez, Avid ; Pajuelo, Monica J. ; Anticona, Cynthia ; Mayta, Holger ; Alva, Alicia ; Solis-Vasquez, Leonardo ; Figueroa, Dante Anibal ; Chavez, Miguel A. ; Lavarello, Roberto ; Castañeda, Benjamin ; Paz-Soldan, Valerie A. ; Checkley, William ; Gilman, Robert H. ; Oberhelman, Richard | Public Library of Science | 2019-03-05T15:23:30ZPneumonia is one of the major causes of child mortality, yet with a timely diagnosis, it is usually curable with antibiotic therapy. In many developing regions, diagnosing pneumonia remains a challenge, due to shortages of medical resources. Lun[...]texto impreso
Tuero, Iskra ; Palma, Sandra ; Cabeza, Franco ; Saleemi, Sarah ; Rodriguez, Silvia ; Gonzales, Isidro ; Mayta, Holger ; Mahanty, Siddhartha ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: The ability of Taenia solium to modulate the immune system likely contributes to their longevity in the human host. We tested the hypothesis that the nature of the immune response is related to the location of parasite and clinical m[...]texto impreso
Tohma, Kentaro ; Saito, Mayuko ; Mayta, Holger ; Zimic, Mirko ; Lepore, Cara J. ; Ford-Siltz, Lauren A. ; Gilman, Robert H. ; Parra, Gabriel I. | American Society of Microbiology | 2018-11-30T02:09:31ZNorovirus, a leading cause of acute gastroenteritis in humans, is a highly diverse virus. Here, we report the complete genome sequence of a nontypeable genogroup II (GII) norovirus that was detected in a symptomatic Peruvian child in 2008. This [...]texto impreso
Cconislla Bello, José L. ; Jacinto, Christian ; Maza, Ily ; Jahuira, Martha ; Pando, Alejandra ; Mayta, Holger ; Valderrama, Ana | Sociedad Química del Perú | 2019-02-22T14:54:03ZLas micropartículas de quitosano entrecruzado (QE1%, QE5%) se prepararon mediante reticulación con el glutaraldehído (GL). Las micropartículas de quitosano cuaternizado (QC) se prepararon mediante cuaternización del grupo amino del quitosano con[...]texto impreso
Gutierrez-Loli, Renzo ; Ferradas, Cusi ; Diestra, Andrea ; Traianou, Aliki ; Bowman, Natalie ; Bok, Jeroen ; Reimer-McAtee, Melissa ; Ramal, Cesar ; Ticona, Eduardo ; Steinberg, Hannah ; Mayta, Holger ; Calderón, Maritza ; Calla-Choque, Jaeson S. ; Sterling, Charles ; Gilman, Robert H. ; Toxoplasmosis Working Group in Peru and Bolivia | American Society of Tropical Medicine and Hygiene | 2019-07-04T16:59:29ZQuantitative polymerase chain reaction (qPCR) for Toxoplasma gondii multicopy genes has emerged as a promising strategy for sensitive detection of parasite DNA. qPCR can be performed from blood samples, which are minimally invasive to collect. H[...]texto impreso
Sánchez, Gerardo J. ; Mayta, Holger ; Pajuelo, Monica J. ; Neira, Karen ; Xiaofang, Liu ; Cabrera, Lilia ; Ballard, Sarah Blythe ; Crabtree, Jean E. ; Kelleher, Dermot ; Cama, Vitaliano ; Bern, Caryn ; Oshitani, Hitoshi ; Gilman, Robert H. ; Saito, Mayuko ; Sapovirus Working Group | Oxford University Press | 2018-11-30T03:10:45ZBackground: Sapovirus is one of the primary viral causes of acute gastroenteritis (AGE), especially where rotavirus vaccination has been implemented. The characteristics and impact of natural infection at the community level, however, have not b[...]texto impreso
Liu, Xiaofang ; Jahuira, Helena ; Gilman, Robert H. ; Alva, Alicia ; Cabrera, Lilia ; Okamoto, Michiko ; Xu, Hang ; Windle, Henry J. ; Kelleher, Dermot ; Varela, Marco ; Verastegui, Manuela ; Calderón, Maritza ; Sanchez, Gerardo ; Sarabia, Vanessa ; Ballard, Sarah B. ; Bern, Caryn ; Mayta, Holger ; Crabtree, Jean E. ; Cama, Vitaliano ; Saito, Mayuko ; Oshitani, Hitoshi | American Society for Microbiology | 2019-02-06T14:45:36ZHuman sapovirus has been shown to be one of the most important etiologies in pediatric patients with acute diarrhea. However, very limited data are available about the causative roles and epidemiology of sapovirus in community settings. A nest[...]texto impreso
Diez-Valcarce, Marta ; Castro, Christina J. ; Marine, Rachel L. ; Halasa, Natasha ; Mayta, Holger ; Saito, Mayuko ; Tsaknaridis, Laura ; Pan, Chao-Yang ; Bucardo, Filemon ; Becker-Dreps, Sylvia ; Lopez, Maria Renee ; Magaña, Laura Cristal ; Ng, Terry Fei Fan ; Vinjé, Jan | Elsevier | 2018-11-30T03:10:47ZBACKGROUND: Sapoviruses are responsible for sporadic and epidemic acute gastroenteritis worldwide. Sapovirus typing protocols have a success rate as low as 43% and relatively few complete sapovirus genome sequences are available to improve curre[...]texto impreso
Mayta, Holger ; Romero, Yomara K. ; Pando, Alejandra ; Verastegui, Manuela ; Tinajeros, Freddy ; Bozo, Ricardo ; Henderson-Frost, Josephine ; Colanzi, Rony ; Flores, Jorge ; Lerner, Richard ; Bern, Caryn ; Gilman, Robert H. | Public Library of Science | 2019-07-04T17:00:16ZBACKGROUND: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either[...]texto impreso
Pisanic, Nora ; Ballard, Sarah-Blythe ; Colquechagua, Fabiola D. ; Francois, Ruthly ; Exum, Natalie ; Yori, Pablo Penataro ; Schwab, Kellogg J. ; Granger, Douglas A. ; Detrick, Barbara ; Olortegui, Maribel Paredes ; Mayta, Holger ; Sánchez, Gerardo J. ; Gilman, Robert H. ; Heaney, Christopher D. ; Vinjé, Jan ; Kosek, Margaret N. | Oxford University Press | 2019-03-05T15:23:28ZBackground: Norovirus is a leading cause of acute gastroenteritis worldwide. Routine norovirus diagnosis requires stool collection. The goal of this study was to develop and validate a noninvasive method to diagnose norovirus to complement stoo[...]texto impreso
Málaga-Machaca, Edith S. ; Romero-Ramirez, Alessandra ; Gilman, Robert H. ; Astupiña-Figueroa, Sofía ; Angulo, Noelia ; Florentini, Alejandro ; Lovon-Luque, Cinthya J. ; Gonza, Remo A. ; Del Carpio-Sanz, Ada ; Cabello, Ines ; Camargo, Rosina ; Recuenco, Fernando ; Barrueta-Soria, Liliam A. ; Verastegui, Manuela R. ; Calderón, Maritza ; Mayta, Holger | Public Library of Science | 2019-01-25T15:28:07ZBACKGROUND: Detection of Trypanosoma cruzi antigens in clinical samples is considered an important diagnostic tool for Chagas disease. The production and use of polyclonal antibodies may contribute to an increase in the sensitivity of immunodiag[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel Angel ; Mayta, Holger ; Marzal, Miguel ; Cangalaya, Carla ; Paredes, Adriana ; Gonzales-Gustavson, Eloy ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2019-02-06T14:53:10ZCysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericysti[...]texto impreso
Noazin, Sassan ; Lee, Jessica A. ; Malaga, Edith S. ; Ayala, Edward Valencia ; Condori, Beth J. ; Roca, Cristian ; Lescano, Andres G. ; Bern, Caryn ; Castillo, Walter ; Mayta, Holger ; Menduiña, Maria Carmen ; Verastegui, Manuela R. ; Tinajeros, Freddy ; Gilman, Robert H. ; Chagas Working Group in Bolivia and Peru | Oxford University Press | 2018-12-03T17:02:50ZBackground: Congenital Trypanosoma cruzi accounts for an estimated 22% of new cases in Latin America. However, neonatal diagnosis is challenging, as 9-month follow-up for IgG testing is poor, qPCR is not routinely performed, and micromethod miss[...]
