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Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]texto impreso
Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]texto impreso
Alva, Alicia ; Cangalaya, Carla ; Quiliano, Miguel ; Krebs, Casey ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:28:05ZParasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lac[...]texto impreso
Cangalaya, Carla ; Bustos, Javier-A. ; Calcina, Juan ; Vargas-Calla, Ana ; Suarez, Diego ; Gonzalez, Armando-E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore-E. ; Garcia, Hector-H. | Public Library of Science | 2019-02-06T14:45:11ZBACKGROUND: Disease manifestations in neurocysticercosis (NCC) are frequently due to inflammation of degenerating Taenia solium brain cysts. Exacerbated inflammation post anthelmintic treatment is associated with leakage of the blood brain barr[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel Angel ; Mayta, Holger ; Marzal, Miguel ; Cangalaya, Carla ; Paredes, Adriana ; Gonzales-Gustavson, Eloy ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2019-02-06T14:53:10ZCysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericysti[...]texto impreso
Cangalaya, Carla ; Bustos, Javier A. ; Calcina, Juan ; Vargas-Calla, Ana ; Mamani, Javier ; Suarez, Diego ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-01-25T16:03:19ZBACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first da[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel A. ; Cangalaya, Carla ; Adrianzen, M. Paz ; Arroyo, Gianfranco ; Calcina, Juan ; Gonzalez, Armando E. ; Garcia, Hector H. ; Guerra-Giraldez, Cristina ; Nash, Theodore E. ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T16:03:22ZBACKGROUND: Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires[...]
