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Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-07-04T16:59:18ZBackground: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable amon[...]texto impreso
Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-12-06T21:02:55ZBACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypo[...]texto impreso
Arroyo, Gianfranco ; Rodriguez, Silvia ; Lescano, Andres G. ; Alroy, Karen A. ; Bustos, Javier A. ; Santivañez, Saul ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2018-11-30T02:09:29ZBackground: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervo[...]texto impreso
Duque, Kevin R. ; Escalaya, Alejandro L. ; Zapata, Willy ; Burneo, Jorge G. ; Bustos, Javier A. ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Elsevier | 2018-11-30T02:09:31ZOBJECTIVE: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance has been raised. In t[...]texto impreso
Garcia, Hector H. ; Gonzales, Isidro ; Bustos, Javier A. ; Saavedra, Herbert ; Gavidia, Martin ; Rodriguez, Lourdes ; Najar, Enrique ; Umeres, Hugo ; Pretell, E. Javier | Elsevier | 2019-02-06T14:59:07Ztexto impreso
Garcia, Hector H. ; Lescano, Andres G. ; Gonzales, Isidro ; Bustos, Javier A. ; Pretell, E. Javier ; Horton, John ; Saavedra, Herbert ; Gonzalez, Armando E. ; Gilman, Robert H. | Oxford University Press | 2019-02-06T14:45:34ZBACKGROUND: The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 antiparasitic drugs improv[...]texto impreso
Taenia solium (the pork tapeworm) is present in most developing countries, where it is a frequent cause of seizures and other neurological disease. Parasitic larvae invade the human brain, establish, and eventually resolve, leaving a calcified s[...]texto impreso
Garcia, Hector H. ; Gonzales, Isidro ; Lescano, Andres G. ; Bustos, Javier A. ; Zimic, Mirko ; Escalante, Diego ; Saavedra, Herbert ; Gavidia, Martin ; Rodriguez, Lourdes ; Najar, Enrique ; Umeres, Hugo ; Pretell, E. Javier | Elsevier | 2020-06-10T18:12:14ZBACKGROUND: Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would increase cystici[...]texto impreso
Bustos, Javier A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Soto-Becerra, Percy ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Nash, Theodore E. ; O'Neal, Seth E. ; Del Brutto, Oscar H. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2020-07-14T00:00:59ZBACKGROUND: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most of the world. Larval cysts in the human brain eventually resolve and either disappear or leave a calcified scar that is associated with seizures. This study asses[...]texto impreso
Herrick, Jesica A. ; Maharathi, Biswajit ; Kim, Jin Suh ; Abundis, Gerardo G. ; Garg, Anjali ; Gonzales, Isidro ; Saavedra, Herbert ; Bustos, Javier A. ; Garcia, Hector H. ; Loeb, Jeffrey A. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T17:17:14ZObjective: We conducted a retrospective, case-control study of neurocysticercosis patients to ascertain early markers that identify subjects likely to develop treatment-resistant seizures. Methods: Clinical histories and imaging studies from 38 [...]texto impreso
Garcia, Hector H. ; Castillo, Yesenia ; Gonzales, Isidro ; Bustos, Javier A. ; Saavedra, Herbert ; Jacob, Louis ; Del Brutto, Oscar H. ; Wilkins, Patricia P. ; Gonzalez, Armando E. ; Gilman, Robert H. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T17:17:15ZOBJECTIVE: To evaluate the diagnostic performance of two commercially available ELISA kits, Novalisa® and Ridascreen® , for the detection of antibodies to Taenia solium, compared to serological diagnosis of neurocysticercosis (NCC) by LLGP-EITB [...]texto impreso
Bustos, Javier A. ; Ninaquispe, Berenice E. ; Rodriguez, Silvia ; Castillo, Yesenia ; Yang, Susan Y. ; Gilman, Robert H. ; Dorny, Pierre ; Gabriel, Sarah ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2019-07-04T17:00:20ZThe pig is the natural intermediate host of Taenia solium, a parasite causing significant burden of disease in both humans and pigs. Porcine cysticercosis is traditionally detected via tongue palpation and slaughterhouse meat inspection, both wi[...]texto impreso
Cangalaya, Carla ; Bustos, Javier A. ; Calcina, Juan ; Vargas-Calla, Ana ; Mamani, Javier ; Suarez, Diego ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-01-25T16:03:19ZBACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first da[...]texto impreso
Bustos, Javier A. ; Garcia, Hector H. ; Del Brutto, Oscar H. | American Society of Tropical Medicine and Hygiene | 2019-01-25T17:00:29ZIntraventricular neurocysticercosis (NCC) is a severe form of NCC requiring prompt diagnosis and treatment. We aimed to assess the reliability of the most recent version of diagnostic criteria for this form of NCC. Two systematic literature revi[...]texto impreso
Bustos, Javier A. ; Garcia, Hector H. ; Del Brutto, Oscar H. | American Society of Tropical Medicine and Hygiene | 2019-01-25T17:00:30Z
