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Heinrich, Erica C. ; Djokic, Matea A. ; Gilbertson, Dillon ; DeYoung, Pamela N. ; Bosompra, Naa-Oye ; Wu, Lu ; Anza-Ramirez, Cecilia ; Orr, Jeremy E. ; Powell, Frank L. ; Malhotra, Atul ; Simonson, Tatum S. | Public Library of Science | 2019-12-06T20:57:47ZImpairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altit[...]texto impreso
Heinrich, Erica C. ; Djokic, Matea A. ; Gilbertson, Dillon ; DeYoung, Pamela N. ; Bosompra, Naa-Oye ; Wu, Lu ; Anza-Ramirez, Cecilia ; Orr, Jeremy E. ; Powell, Frank L. ; Malhotra, Atul ; Simonson, Tatum S. | Public Library of Science | 2019-07-04T16:59:25ZImpairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altit[...]texto impreso
Heinrich, Erica C. ; Wu, Lu ; Lawrence, Elijah S. ; Cole, Amy M. ; Anza-Ramirez, Cecilia ; Villafuerte, Francisco C. ; Simonson, Tatum S. | Wiley | 2019-07-04T16:59:37ZEGLN1 encodes the hypoxia-inducible factor (HIF) pathway prolyl hydroxylase 2 (PHD2) that serves as an oxygen-sensitive regulator of HIF activity. The EGLN1 locus exhibits a signature of positive selection in Tibetan and Andean populations and i[...]texto impreso
Heinrich, Erica C. ; Gaio, Eduardo ; Powell, Frank L. ; Macarlupu, Jose Luis ; Anza-Ramirez, Cecilia ; Corante, Noemi ; Vizcardo-Galindo, Gustavo ; Villafuerte, Francisco C. ; Simonson, Tatum S. | Federation of American Society of Experimental Biology | 2019-02-22T14:54:31ZMultiple adaptive phenotypes for high-altitude and hypoxic stress have developed by distinct evolutionary trajectories in highland populations. For example, considerable variation is observed in the hypoxic ventilatory response (HVR) of Tibetans[...]texto impreso
Heinrich, Erica C. ; Orr, Jeremy E. ; Gilbertson, Dillon ; Anza-Ramirez, Cecilia ; DeYoung, Pamela N. ; Djokic, Matea A. ; Corante, Noemi ; Vizcardo-Galindo, Gustavo ; Macarlupu, Jose L. ; Gaio, Eduardo ; Powell, Frank L. ; Malhotra, Atul ; Villafuerte, Francisco C. ; Simonson, Tatum S. | Frontiers Media | 2020-07-14T00:01:15ZAndean highlanders are challenged by chronic hypoxia and many exhibit elevated hematocrit (Hct) and blunted ventilation compared to other high-altitude populations. While many Andeans develop Chronic Mountain Sickness (CMS) and excessive erythro[...]
