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Gutiérrez-Zugasti, Igor ; García-Escárzaga, Asier ; Martín Chivelet, Javier ; González-Morales, Manuel R. | SAGE Publishing | 2015Changes in oxygen isotope ratios from shell carbonates are mainly dependent on sea surface temperature, which enables the estimation of temperatures during periods of shell growth and helps to determine the season of the year when the mollusk di[...]texto impreso
Vela, Laura ; Caballero, Iván ; Fang, Leiping ; Liu, Qin ; Ramón Olayo, Fernando Antonio ; Díez, Emilio ; Frailes, Maite de los | SAGE Publishing | 2015Multiple sclerosis (MS) is an autoimmune neurodegenerative disease that involves activation of T cells, microglia, and astrocytes. There is a clear unmet medical need for MS, as current therapies reduce the relapse rate, but are unable to preven[...]texto impreso
Cleofé Zapatero, María ; Pérez, Paloma ; Vázquez, María Jesús ; Colmenarejo Sánchez, Gonzalo ; Frailes, Maite de los ; Ramón Olayo, Fernando Antonio | SAGE Publishing | 2015Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine associated with multiple diseases, including neurodegenerative disorders. With the ultimate goal of providing novel chemotypes as starting points for development of disea[...]texto impreso
Background: The aim was to assess the impact of 5- and 10-degree rotations in the optical quality of a trifocal toric intraocular lens with different amounts of cylinder. Methods: Two Physiol Toric intraocular lenses with 1.5 and 3.0 D of cylind[...]