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Contact evaluation and isoniazid preventive therapy among close and household contacts of tuberculosis patients in Lima, Peru: an analysis of routine data.

Otero, Larissa ; Battaglioli, Tullia ; Rios, Julia ; De la Torre, Zayda ; Trocones, Nayda ; Ordonez, Cielo ; Seas, Carlos ; Van der Stuyft, Patrick | Wiley | 2019-12-06T21:04:46Z

OBJECTIVE: Contacts of pulmonary tuberculosis (TB) cases are at high risk of TB infection and progression to disease. Close and household contacts and those

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Mycobacterium tuberculosis-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting.

Sudbury, Eva L. ; Otero, Larissa ; Tebruegge, Marc ; Messina, Nicole L. ; Seas, Carlos ; Montes, Martin ; Rios, Julia ; Germano, Susie ; Gardiner, Kaya ; Clifford, Vanessa ; Gotuzzo, Eduardo ; Curtis, Nigel | Elsevier | 2019-12-06T20:57:48Z

The tuberculin skin test and interferon-gamma release assays have limitations in diagnosing tuberculosis (TB), particularly in children. This study investigated the performance of candidate M. tuberculosis-specific cytokine biomarkers for TB i[...]

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