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Gomes, Cláudia ; Ruiz-Roldan, Lidia ; Mateu, Judit ; Ochoa, Theresa J. ; Ruiz, Joaquim | Nature Research | 2019-07-04T16:59:21ZDespite azithromycin being used in some countries to treat infections caused by Gram-negative pathogens, no resistance breakpoint for Escherichia coli exists. The aim of this study was to analyse the levels and mechanisms of azithromycin resista[...]texto impreso
Gomes, Cláudia ; Pons, Maria J. ; Del Valle Mendoza, Juana Mercedes ; Ruiz, Joaquim | BioMed Central Ltd. | 2017-11-08T22:20:47ZCarrion’s disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion’s disease is a biphasic illness; in the acute phase the case-fa[...]texto impreso
Horna, Gertrudis ; Velasquez, Jorge ; Fernandez, Nathaly ; Tamariz, Jesus ; Ruiz, Joaquim | Elsevier | 2019-01-25T16:59:36ZOBJECTIVES: The aim of this study was to characterise a KPC-carrying Klebsiella pneumoniae isolate from a Peruvian hospital setting. METHODS: The identity of the isolate was confirmed by amplification and sequencing of the 16S rRNA gene, and the[...]texto impreso
Medina, Anicia M. ; Rivera, Fulton P. ; Pons, Maria J. ; Riveros, Maribel ; Gomes, Cláudia ; Bernal, Maria ; Meza, Rina ; Maves, Ryan C. ; Huicho, Luis ; Chea-Woo, Elsa ; Lanata, Claudio F. ; Gil, Ana I. ; Ochoa, Theresa J. ; Ruiz, Joaquim | Oxford University Press | 2019-02-06T14:57:42ZBACKGROUND: Antibiotic resistance is increasing worldwide, being of special concern in low- and middle-income countries. The aim of this study was to determine the antimicrobial susceptibility and mechanisms of resistance in 205 enterotoxigenic [...]texto impreso
Martinez-Puchol, Sandra ; Gomes, Cláudia ; Pons, Maria J. ; Ruiz-Roldan, Lidia ; Torrents de la Pena, Alba ; Ochoa, Theresa J. ; Ruiz, Joaquim | Wiley | 2019-02-06T14:52:12ZFurazolidone-resistant mutants were obtained from four clinical isolates of diarrhoeagenic Escherichia coli. The stability of the resistance and the frequency of mutation were established. The minimal inhibitory concentration of furazolidone, ni[...]texto impreso
Mosquito, Susan ; Pons, Maria J. ; Riveros, Maribel ; Ruiz, Joaquim ; Ochoa, Theresa J. | Hindawi Publishing Corporation | 2019-02-06T14:57:41ZConventionally, in Escherichia coli, phylogenetic groups A and B1 are associated with commensal strains while B2 and D are associated with extraintestinal strains. The aim of this study was to evaluate diarrheagenic (DEC) and commensal E. coli[...]texto impreso
Pantenburg, Birte ; Ochoa, Theresa J. ; Ecker, Lucie ; Ruiz, Joaquim | American Society of Tropical Medicine and Hygiene | 2020-06-10T18:11:36ZChildhood diarrhea is an important cause of malnutrition, which can be worsened when caretakers limit nutritional support. We queried 390 caregivers and their children in a peri-urban community in Lima, Peru regarding general perceptions of feed[...]texto impreso
Horna, Gertrudis ; Amaro, Catherine ; Palacios, Aida ; Guerra, Humberto ; Ruiz, Joaquim | Nature Research | 2019-08-08T15:23:48ZThe type III secretion system of Pseudomonas aeruginosa is an important virulence factor contributing to the cytotoxicity and the invasion process of this microorganism. The current study aimed to determine the presence of the exoU+/exoS+ genoty[...]texto impreso
Pons, Maria J. ; Gomes, Cláudia ; Aguilar, Ruth ; Barrios, Diana ; Aguilar-Luis, Miguel Angel ; Ruiz, Joaquim ; Dobaño, Carlota ; Del Valle-Mendoza, Juana ; Moncunill, Gemma | Public Library of Science | 2017-10-09T17:11:19ZAnalysis of immune responses in Bartonella bacilliformis carriers are needed to understand acquisition of immunity to Carrion’s disease and may allow identifying biomarkers associated with bacterial infection and disease phases. Serum samples fr[...]texto impreso
Durand, David ; Alvarez, Daniela ; Diaz, David ; Mercado, Erik ; Ruiz, Joaquim ; Ochoa, Theresa J. | Elsevier Doyma | 2020-07-14T00:01:08ZINTRODUCTION: We evaluated the presence of sIgA in saliva, versus Escherichia coli secreted proteins (Esp) related to the type III secretion system (T3SS), and its semi-quantitative concentration in children under 2 years-old (no longer breastfe[...]texto impreso
Horna, Gertrudis ; López, María ; Guerra, Humberto ; Saenz, Yolanda ; Ruiz, Joaquim | Nature Research | 2018-11-30T17:17:14ZMexAB-OprM and MexEF-OprN are Pseudomonas aeruginosa efflux pumps involved in the development of antibiotic resistance. Several studies developed with laboratory strains or using a few clinical isolates have reported that the regulation system o[...]texto impreso
Gomes, Cláudia ; Martinez-Puchol, Sandra ; Palma, Noemi ; Horna, Gertrudis ; Ruiz-Roldan, Lidia ; Pons, Maria J. ; Ruiz, Joaquim | Taylor & Francis | 2019-01-25T17:00:26ZFrom its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Gram-positive microorganisms, this antimicrobial family ha[...]texto impreso
Riveros, Maribel ; Garcia, Wilfredo ; García, Coralith ; Durand, David ; Mercado, Erik ; Ruiz, Joaquim ; Ochoa, Theresa J. | American Society of Tropical Medicine and Hygiene | 2019-01-25T15:28:06ZEscherichia coli is an important cause of Gram-negative bacteremia. The aim of this study was to characterize at the molecular and phenotypic levels E. coli strains belonging to different diarrheagenic pathotypes [diarrheagenic E. coli (DEC)] is[...]texto impreso
Ulloa, Gabriela M. ; Vásquez-Achaya, Fernando ; Gomes, Cláudia ; Del Valle, Luis J. ; Ruiz, Joaquim ; Pons, Maria J. ; Del Valle Mendoza, Juana | American Society of Tropical Medicine and Hygiene | 2018-11-30T17:17:16ZCarrion's disease is a neglected, vector-borne illness that affects Colombia, Ecuador, and especially Peru. The phlebotomine sand flies Lutzomyia verrucarum and Lutzomyia peruensis are the main illness vectors described, although other species m[...]texto impreso
Mercado, Erik-H. ; Piscoche, Cristian ; Contreras, Carmen ; Durand, David ; Riveros, Maribel ; Ruiz, Joaquim ; Ochoa, Theresa-J. | Elsevier | 2019-02-06T14:45:55ZEPEC is an attaching and effacing diarrheal pathogen that carries a large pathogenicity island, locus for enterocyte effacement (LEE). Recently, the pathogenicity island PAI O-122 was described among non-LEE effectors and found to be associated [...]
