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Kushawah, G. ; Hernandez-Huertas, L. ; Abugattas-Nuñez del Prado, J. ; Martinez-Morales, J.R. ; DeVore, M.L. ; Hassan, H. ; Moreno-Sanchez, I. ; Tomas-Gallardo, L. ; Diaz-Moscoso, A. ; Monges, D.E. ; Guelfo, J.R. ; Theune, W.C. ; Brannan, E.O. ; Wang, W. ; Corbin, T.J. ; Moran, A.M. ; Sánchez Alvarado, A. ; Malaga-Trillo, E. ; Takacs, C.M. ; Bazzini, A.A. ; Moreno-Mateos, M.A. | Cell Press | 2020-12-14T16:06:27ZThe development of mRNA knockdown technologies for use in vertebrate organisms such as zebrafish has been limited. Kushawah et al. establish CRISPR-RfxCas13d as an efficient, specific, cost-effective, and straightforward method for the systemati[...]texto impreso
Tume, L. ; Gallo, Carla ; Malaga-Trillo, E. ; Poletti, Giovanni ; Rojas, R. ; Vaisberg, A. J. | Federation of American Society of Experimental Biology | 2019-01-25T16:20:58ZBackground: Schizophrenia is a severe mental disorder that affects approximately 1% of the population. The main symptom is psychosis in which thought and emotions are impaired. Current pharmacological treatments for schizophrenia are partially e[...]texto impreso
Pinzón-Olejua, A. ; Welte, C. ; Abdesselem, H. ; Malaga-Trillo, E. ; Stuermer, C.A.O. | BMC | 2020-06-10T18:12:16ZBackground: As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b. The shared presence of four specific amino acid motifs-M1 to M4-in the N-terminal region of mammalian RTN4, and zebra[...]
