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Reis-Cunha, J.L. ; Rodrigues-Luiz, G.F. ; Valdivia, H.O. ; Baptista, R.P. ; Mendes, T.A.O. ; Loss de Morais, G. ; Guedes, R. ; Macedo, A.M. ; Bern, C. ; Gilman, R.H. ; Talavera Lopez, C. ; Andersson, B. ; Vasconcelos, A.T. ; Bartholomeu, D.C. | BMC | 2019-04-24T18:23:51ZBackground: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. CL Brener, the reference strain of the T. cruzi genome project, is a hybrid with a genome assembled[...]texto impreso
Gutierrez-Loli, R. ; Ferradas, C. ; Diestra, A. ; Traianou, A. ; Bowman, N. ; Bok, J. ; Reimer-McAtee, M. ; Ramal, C. ; Ticona, E. ; Steinberg, H. ; Mayta, H. ; Calderón, M. ; Calla-Choque, J.S. ; Sterling, C. ; Gilman, R.H. ; Pinedo, L.C. ; Valencia, G. ; Sánchez, L. ; Málaga, E. ; Zhu, D. ; Jiménez, J. ; Bern, C. ; Angulo, N. ; Schiaffino, F. ; Acosta, J. ; Holtz, M. ; Clark, D. ; Clark, T. ; Trompeter, G. ; Choi, J. ; Gandarilla, O. ; Dorn, M. ; Fortuny, E. ; Galdos, G. ; Colanzi, R. | American Society of Tropical Medicine and Hygiene | 2019-12-06T20:57:49ZQuantitative polymerase chain reaction (qPCR) for Toxoplasma gondii multicopy genes has emerged as a promising strategy for sensitive detection of parasite DNA. qPCR can be performed from blood samples, which are minimally invasive to collect. H[...]texto impreso
Waltmann, A. ; Willcox, A.C. ; Balasubramanian, S. ; Borrini Mayori, K. ; Mendoza Guerrero, S. ; Salazar Sanchez, R.S. ; Roach, J. ; Condori Pino, C. ; Gilman, R.H. ; Bern, C. ; Juliano, J.J. ; Levy, M.Z. ; Meshnick, S.R. ; Bowman, N.M. | Public Library of Science | 2019-12-06T20:57:46ZTriatomine vectors transmit Trypanosoma cruzi, the etiological agent of Chagas disease in humans. Transmission to humans typically occurs when contaminated triatomine feces come in contact with the bite site or mucosal membranes. In the Southern[...]texto impreso
Mayta, H. ; Romero, Y.K. ; Pando, A. ; Verastegui, M. ; Tinajeros, F. ; Bozo, R. ; Henderson-Frost, J. ; Colanzi, R. ; Flores, J. ; Lerner, R. ; Bern, C. ; Gilman, R.H. ; Chagas Working Group in Peru and Bolivia | Public Library of Science | 2019-12-06T21:04:40ZBackground: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either[...]texto impreso
Labayo, H.K.M. ; Pajuelo, M.J. ; Tohma, K. ; Ford-Siltz, L.A. ; Gilman, R.H. ; Cabrera, L. ; Mayta, H. ; Sanchez, G.J. ; Cornejo, A.T. ; Bern, C. ; Dapat, C. ; Nochi, T. ; Parra, G.I. ; Oshitani, H. ; Saito, M. | Lancet Publishing Group | 2020-12-14T16:06:28ZBackground: Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diar[...]texto impreso
Alroy, K.A. ; Huang, C. ; Gilman, R.H. ; Quispe-Machaca, V.R. ; Marks, M.A. ; Ancca-Juarez, J. ; Hillyard, M. ; Verastegui, M. ; Sanchez, G. ; Cabrera, L. ; Vidal, E. ; Billig, E.M.W. ; Cama, V.A. ; Naquira, C. ; Bern, C. ; Levy, M.Z. ; Working Group on Chagas Disease in Peru | Public Library of Science | 2019-04-24T18:23:55ZVector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and [...]texto impreso
Noazin, S. ; Lee, J.A. ; Malaga, E.S. ; Valencia Ayala, E. ; Condori, B.J. ; Roca, C. ; Lescano, A.G. ; Bern, C. ; Castillo, W. ; Mayta, H. ; Menduiña, M.C. ; Verástegui, M.R. ; Tinajeros, F. ; Gilman, R.H. | Oxford University Press | 2019-12-06T21:02:59ZBackground Congenital Trypanosoma cruzi infection accounts for an estimated 22% of new cases of Chagas disease in Latin America. However, neonatal diagnosis is challenging, as 9-month follow-up for immunoglobulin G testing is poor, quantitative [...]
