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Lacerda, Marcus V. G. ; Llanos-Cuentas, Alejandro ; Krudsood, Srivicha ; Lon, Chanthap ; Saunders, David L. ; Mohammed, Rezika ; Yilma, Daniel ; Batista Pereira, Dhelio ; Espino, Fe E. J. ; Mia, Reginaldo Z. ; Chuquiyauri, Raúl ; Val, Fernando ; Casapía, Martin ; Monteiro, Wuelton M. ; Brito, Marcelo A. M. ; Costa, Monica R. F. ; Buathong, Nillawan ; Noedl, Harald ; Diro, Ermias ; Getie, Sisay ; Wubie, Kalehiwot M. ; Abdissa, Alemseged ; Zeynudin, Ahmed ; Abebe, Cherinet ; Tada, Mauro S. ; Brand, Francoise ; Beck, Hans-Peter ; Angus, Brian ; Duparc, Stephan ; Kleim, Jorg-Peter ; Kellam, Lynda M. ; Rousell, Victoria M. ; Jones, Sion W. ; Hardaker, Elizabeth ; Mohamed, Khadeeja ; Clover, Donna D. ; Fletcher, Kim ; Breton, John J. ; Ugwuegbulam, Cletus O. ; Green, Justin A. ; Koh, Gavin C. K. W. | Massachusetts Medical Society | 2019-07-04T17:00:24ZBACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical cure"). Tafenoquine is a single-dose 8[...]texto impreso
Llanos-Cuentas, Alejandro ; Lacerda, Marcus V. G. ; Hien, Tran T. ; Velez, Ivan D. ; Namaik-Larp, Chayadol ; Chu, Cindy S. ; Villegas, Maria F. ; Val, Fernando ; Monteiro, Wuelton M. ; Brito, Marcelo A. M. ; Costa, Monica R. F. ; Chuquiyauri, Raúl ; Casapía, Martin ; Nguyen, Chau H. ; Aruachan, Sandra ; Papwijitsil, Ratchadaporn ; Nosten, Francois H. ; Bancone, Germana ; Angus, Brian ; Duparc, Stephan ; Craig, Graham ; Rousell, Victoria M. ; Jones, Sion W. ; Hardaker, Elizabeth ; Clover, Donna D. ; Kendall, Lindsay ; Mohamed, Khadeeja ; Koh, Gavin C. K. W. ; Wilches, Viviana M. ; Breton, John J. ; Green, Justin A. | Massachusetts Medical Society | 2019-07-04T17:01:20ZBACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." METHODS: We performed a phase 3, pros[...]
