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Biphasic in vitro maturation (CAPA-IVM) specifically improves the developmental capacity of oocytes from small antral follicles

Sánchez, F. ; Le, A.H. ; Ho, V.N.A. ; Romero, S. ; Van Ranst, H. ; De Vos, M. ; Gilchrist, R.B. ; Ho, T.M. ; Vuong, L.N. ; Smitz, J. | Springer | 2019-12-06T21:04:52Z

Purpose: To investigate the effectiveness of a biphasic IVM culture strategy at improving IVM outcomes in oocytes from small follicles (

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DNA methylation and mRNA expression of imprinted genes in blastocysts derived from an improved in vitro maturation method for oocytes from small antral follicles in polycystic ovary syndrome patients.

Saenz-de-Juano, M. D. ; Ivanova, E. ; Romero, S. ; Lolicato, F. ; Sánchez, F. ; Van Ranst, H. ; Krueger, F. ; Segonds-Pichon, A. ; De Vos, M. ; Andrews, S. ; Smitz, J. ; Kelsey, G. ; Anckaert, E. | Oxford University Press | 2019-12-06T21:04:48Z

STUDY QUESTION: Does imprinted DNA methylation or imprinted gene expression differ between human blastocysts from conventional ovarian stimulation (COS) and an optimized two-step IVM method (CAPA-IVM) in age-matched polycystic ovary syndrome (P[...]

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