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Varas, Javier ; Graumann, K. ; Osman, Kim ; Pradillo Orellana, Mónica ; Evans, David E. ; Santos Coloma, Juan Luis ; Armstrong, Susan J. | John Wiley & Sons | 2015The movement of chromosomes during meiosis involves the location of their telomeres at the inner surface of the nuclear envelope (NE). Sad1/UNC-84 (SUN)-domain proteins are inner NE proteins that are part of complexes linking cytoskeletal elemen[...]texto impreso
Oliver Velasco, Cecilia ; Santos Coloma, Juan Luis ; Padrillo Orellana, Mónica | Genetics Society of America | 2016-10RNA-directed DNA methylation (RdDM) pathway is important for the transcriptional repression of transposable elements and for heterochromatin formation. Small RNAs are key players in this process throughout a feedback with both DNA and histone me[...]texto impreso
Varas, Javier ; Sánchez Morán, Eugenio ; Copenhaver, Juan ; Santos Coloma, Juan Luis ; Pradillo Orellana, Mónica | PLOS | 2015-07-06Chromatin Assembly Factor 1 (CAF-1) is a histone chaperone that assembles acetylated histones H3/H4 onto newly synthesized DNA, allowing the de novo assembly of nucleosomes during replication. CAF-1 is an evolutionary conserved heterotrimeric pr[...]texto impreso
Parra Núñez, Pablo ; Pradillo Orellana, Mónica ; Santos Coloma, Juan Luis | University of Melbourne | 2019-01-09Polyploid organisms provide additional opportunities to study meiosis in a more complex context since more than two potential homologous chromosomes are available. When the chromosome complement of a diploid individual is duplicated, each chromo[...]texto impreso
Gallego Rodríguez, Francisco Javier ; Cuñado Rodríguez, Nieves ; Figueiras Merino, Ana Margarita ; Benito Jiménez, Cesar ; Rueda Muñoz De San Pedro, Julia ; Naranjo Pompa, Tomas ; Díez Sancho, Manuel ; de Arana Montes, María del Pilar ; Callejas Hervás, Carmen ; de la Peña Gómez, Alicia ; González Sánchez, Mónica ; Espino Nuño, Francisco Javier ; Vega Melero,, Juan Manuel ; Santos Coloma, Juan Luis ; Beroiz Remirez, Beatriz ; Muñoz Martín, Gloria ; Barrios Díaz, José ; Moreno Ortiz, María Del Carmen ; Linacero de la Fuente, M Rosario | 2017-07-31texto impreso
Linacero de la Fuente, Rosario ; Gallego Rodríguez, Francisco Javier ; Callejas Hervás, Carmen ; Arana Montes, María del Pilar ; Beroiz, Beatriz ; Cuñado Rodríguez, Nieves ; Díez Sancho, Manuel ; Espino Nuño, Francisco Javier ; Figueiras Merino, Ana Margarita ; González Sánchez, Mónica ; Naranjo Pompa, Tomas ; Ochando González, María Dolores ; de la Peña Gómez, Alicia ; Pradillo Orellana, Mónica ; Rueda Muñoz De San Pedro, Julia ; Santos Coloma, Juan Luis ; Vega Melero, Juan Manuel ; Barrios Díaz, José ; de la Cruz Jiménez, Monica ; Moreno Ortiz, María Del Carmen | 2016-02texto impreso
Hampel, M. ; Alonso, E. ; Aparicio, I. ; Santos Coloma, Juan Luis ; Leaver, M. | The American Society for Biochemistry and Molecular Biology | 2015-02Pharmaceuticals are pseudopersistent aquatic pollutants with unknown effects at environmentally relevant concentrations. Atlantic salmon (Salmo salar) were exposed to Acetaminophen: 54.77 ± 34.67; Atenolol: 11.08 ± 7.98, and Carbamazepine: 7.85 [...]texto impreso
Linacero de la Fuente, M. Rosario ; Pradillo Orellana, Mónica ; Gallego Rodríguez, Francisco Javier ; Espino Nuño, Francisco Javier ; González Sánchez, Mónica ; Arana Montes, María del Pilar De ; Rueda Muñoz De San Pedro, Julia ; Callejas Hervás, Carmen ; Figueiras Merino, Ana Margarita ; Díez Sancho, Manuel ; Peña Gómez, Alicia De La ; Naranjo Pompa, Tomas ; Vega Melero, Juan Manuel ; Cuñado Rodríguez, Nieves ; Barrios Díaz, José ; Moreno Ortiz, María Del Carmen ; Santos Coloma, Juan Luis ; Beroiz Remirez, Beatriz ; Benito Jiménez, Cesar | 2018-10-01Se ha diseñado una actividad: la caracterización molecular de la mutación de un gen que modifica el color de los ojos en Drosophila melanogaster, partiendo de un carácter morfológico, el color de los ojos, se obtendrá la secuencia del gen respon[...]texto impreso
During meiosis, accurate segregation of chromosomes requires the formation of bivalents at metaphase I. In autopolyploids, there are more than two copies of each chromosome with the same chance to form chiasmata at meiosis. This leads to the for[...]texto impreso
Pradillo Orellana, Mónica ; Knoll, Alexander ; Oliver Velasco, Cecilia ; Varas, Javier ; Corredor Molguero, Eduardo ; Puchta, Olger ; Santos Coloma, Juan Luis | Frontiers Media | 2015-12-01Maintenance and precise regulation of sister chromatid cohesion is essential for faithful chromosome segregation during mitosis and meiosis. Cohesin cofactors contribute to cohesin dynamics and interact with cohesin complexes during cell cycle. [...]texto impreso
Oliver, Cecilia ; Pradillo Orellana, Mónica ; Jover-Gil, Sara ; Santos Coloma, Juan Luis ; Cuñado Rodríguez, Nieves ; Ponce, María Rosa | Springer Nature | 2017-08-24MicroRNAs (miRNAs) are ~22-nt single-stranded noncoding RNAs with regulatory roles in a wide range of cellular functions by repressing eukaryotic gene expression at a post-transcriptional level. Here, we analyzed the effects on meiosis and ferti[...]texto impreso
Chromatin Assembly Factor 1 (CAF-1) is an evolutionary conserved heterotrimeric chaperone complex that facilitates the incorporation of histones H3 and H4 onto newly synthesized DNA. We demonstrate here that the mutant deficient for the large su[...]
