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Beltrán Beck, Beatriz ; Romero Martínez, Beatriz ; Sevilla, Iker A ; Barasona, Jose A ; Garrido, Joseba M ; González-Barrio, David ; Díez Delgado, Iratxe ; Minguijón, Esmeralda ; Casal, Carmen ; Vicente, Joaquín ; Gortazar, Christian ; Aranaz Martín, Alicia | American Society for Microbiology | 2014-01Wildlife vaccination is increasingly being considered as an option for tuberculosis control. We combined data from laboratory trials and an ongoing field trial to assess the risk of an oral Mycobacterium bovis BCG vaccine and a prototype heat-in[...]texto impreso
De la Fuente, Jose ; Díez Delgado, Iratxe ; Contreras, Marinela ; Vicente, Joaquín ; Cabezas Cruz, Alejandro ; Tobes, Raquel ; Manrique, Marina ; López, Vladimir ; Romero Martínez, Beatriz ; Bezos Garrido, Javier ; Domínguez Rodríguez, Lucas ; Sevilla, Iker A ; Garrido, Joseba M ; Juste, Ramón ; Madico, Guillermo ; Jones-López, Edward ; Gortazar, Christian | Public Library Science | 2015-11Mycobacteria of the Mycobacterium tuberculosis complex (MTBC) greatly affect humans and animals worldwide. The life cycle of mycobacteria is complex and the mechanisms resulting in pathogen infection and survival in host cells are not fully unde[...]texto impreso
De la Fuente, Jose ; Díez Delgado, Iratxe ; Contreras, Marinela ; Vicente, Joaquín ; Cabezas Cruz, Alejandro ; Manrique, Marina ; Tobes, Raquel ; López, Vladimir ; Romero, Beatriz ; Domínguez Rodríguez, Lucas ; Garrido, Joseba M ; Juste, Ramón ; Gortazar, Christian | American Society for Microbiology | 2015-06-25Here we report the complete genome sequences of field isolates of Mycobacterium bovis and the related mycobacterial species, Mycobacterium caprae. The genomes of three M. bovis (MB1, MB3, MB4) and one M. caprae (MB2) field isolates with differen[...]texto impreso
Gortazar, Christian ; Beltrán-Beck, Beatriz ; Garrido, Joseba M ; Aranaz Martín, Alicia ; Sevilla, Iker A ; Boadella, Mariana ; Lyashchenko, Konstantin P ; Galindo, Ruth C ; Montoro, Vidal ; Domínguez Rodríguez, Lucas ; Juste, Ramón ; De la Fuente, Jose | BioMedCentral | 2014-04-26BACKGROUND Field vaccination trials with Mycobacterium bovis BCG, an attenuated mutant of M. bovis, are ongoing in Spain, where the Eurasian wild boar (Sus scrofa) is regarded as the main driver of animal tuberculosis (TB). The oral baiting str[...]texto impreso
Beltrán-Beck, Beatriz ; De la Fuente, Jose ; Garrido, Joseba M ; Aranaz Martín, Alicia ; Sevilla, Iker ; Villar, Margarita ; Boadella, Mariana ; Galindo, Ruth C ; Pérez de la Lastra, José M ; Moreno Cid, Juan A ; Fernández de Mera, Isabel G ; Alberdi, Pilar ; Santos, Gracia ; Ballesteros, Cristina ; Lyashchenko, Konstantin P ; Minguijón, Esmeralda ; Romero Martínez, Beatriz ; Juan Ferré, Lucia de ; Domínguez Rodríguez, Lucas ; Juste, Ramón ; Gortazar, Christian | Public Library Science | 2014Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model fo[...]texto impreso
Beltrán-Beck, Beatriz ; Romero Martínez, Beatriz ; Boadella, Mariana ; Casal, Carmen ; Bezos Garrido, Javier ; Mazariegos Martínez-Peñalver, María ; Martín, MariPaz ; Galindo, Ruth C ; Pérez de la Lastra, José M ; Villar, Margarita ; Garrido, Joseba M ; Sevilla, Iker A ; Asensio, Fernando ; Sicilia, Javier ; Lyashchenko, Konstantin P ; Domínguez Rodríguez, Lucas ; Juste, Ramón A ; De la Fuente, Jose ; Gortazar, Christian | American Society for Microbiology | 2014-08Mycobacterium bovis causes animal tuberculosis (TB) in cattle, humans, and other mammalian species, including pigs. The goal of this study was to experimentally assess the responses of pigs with and without a history of tonsillectomy to oral vac[...]
