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Mota Martorell, Natalia ; Jové, Mariona ; Pradas, Irene ; Berdún, Rebeca ; Sánchez, Isabel ; Naudi, Alba ; Gari, Eloi ; Barja de Quiroga, Gustavo ; Pamplona, Reinald | Springer | 2020-06Species longevity varies significantly across animal species, but the underlying molecular mechanisms remain poorly understood. Recent studies and omics approaches suggest that phenotypic traits of longevity could converge in the mammalian targe[...]texto impreso
Jové, Mariona ; Mate Otaño, Ianire ; Naudi, Alba ; Mota Martorell, Natalia ; Portero Otín, Manuel ; Fuente del Rey, Mónica de la ; Pamplona, Reinald | The Gerontological Society of America | 2016A molecular description of the mechanisms by which aging is produced is still very limited. Here, we have determined the plasma metabolite profile by using high-throughput metabolome profiling technologies of 150 healthy humans ranging from 30 t[...]texto impreso
Galván, Ismael ; Naudi, Alba ; Erritzøe, Johannes ; Møller, Anders P. ; Barja de Quiroga, Gustavo ; Pamplona, Reinald | Wiley | 2015-10The evolution of lifespan is a central question in evolutionary biology, begging the question why there is so large variation among taxa. Specifically, a central quest is to unravel proximate causes of ageing. Here, we show that the degree of un[...]texto impreso
Mota-Martorell, Natalia ; Jové, Mariona ; Pradas, Irene ; Sánchez, Isabel ; Gómez, José ; Naudi, Alba ; Barja de Quiroga, Gustavo ; Pamplona, Reinald | Elsevier | 2020-04-20Mitochondrial reactive oxygen species (ROS) production, specifically at complex I (Cx I), has been widely suggested to be one of the determinants of species longevity. The present study follows a comparative approach to analyse complex I in hear[...]
