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Dominguez Godínez, Carmen Olalla ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | Mary Ann Liebert | 2018-03-01Purpose: The aim of this study was to evaluate the ability to uptake and to deliver diquafosol from commercial contact lenses (CLs) and its effect on tear secretion. Methods: For both in vitro and in vivo experiments, two commercial silicone hyd[...]texto impreso
Navarro Gil, Francisco Javier ; Huete Toral, Fernando ; Crooke, Almudena ; Dominguez Godínez, Carmen Olalla ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | American Society for Pharmacology and Experimental Therapeutics | 2019-10Melatonin has been shown to enhance tear secretion associated with dinucleotide diadenosine tetraphosphate. This study investigated the isolated action of melatonin and its analogs, agomelatine, N-butanoyl-2-(2-methoxy-6H-isoindolo[2,1-a]indol-1[...]texto impreso
Dominguez Godínez, Carmen Olalla ; Martin-Gil, Alba ; Carracedo Rodríguez, Juan Gonzalo ; Guzmán Aranguez, Ana María ; Gonzalez-Meijome, Jose Manuel ; Pintor, Jesús | Spanish General Council of Optometrists | 2013-10Purpose To evaluate the possible use of soft contact lenses (CL) to improve the secretagogue role of diadenosine tetraphosphate (Ap4A) promoting tear secretion. Methods Two conventional hydrogel CL (Omafilcon A and Ocufilcon D) and two silico[...]
