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Lamana, Amalia ; Villares, Ricardo ; Seoane Valiño, Iria V. ; Andrés, Nuria ; Lucas, Pilar ; Emery, Paul ; Vital, Edward M. ; Triguero-Martínez, Ana ; Márquez, Ana ; Ortiz, Ana M. ; Maxime, Robin ; Martínez, Carmen ; Martín, Javier ; Gomáriz, Rosa P. ; Ponchel, Frederique ; González-Álvaro, Isidoro ; Mellado, Mario | Frontiers Media | 2020-06-26Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show mode[...]texto impreso
Pérez García, Selene ; Carrión Caballo, Mar ; Gutiérrez-Cañas, Irene ; Villanueva-Romero, Raúl ; Castro Moreno, David ; Martínez, Carmen ; González-Álvaro, Isidoro ; Blanco, Francisco J. ; Juarranz Moratilla, Yasmina ; Gomáriz, Rosa P. | MDPI | 2019-12-22The extracellular matrix (ECM) is a complex and specialized three-dimensional macromolecular network, present in nearly all tissues, that also interacts with cell surface receptors on joint resident cells. Changes in the composition and physical[...]texto impreso
Seoane Valiño, Iria V. ; Martínez, Carmen ; Garcia-Vicuña, Rosario ; Ortiz, Ana M. ; Juarranz Moratilla, Yasmina ; Talayero, Vanessa C. ; González-Álvaro, Isidoro ; Gomáriz, Rosa P. ; Lamana, Amalia | Nature Publishing Group | 2018-02-01We previously reported that early arthritis (EA) patients with low vasoactive intestinal peptide (VIP) serum levels demonstrate a worse clinical disease course. In this study, we analysed whether variants in the VIP gene correlated with its seru[...]texto impreso
Valiño Seoane, Iria ; Tomero, Eva ; Martínez, Carmen ; Garcia-Vicuña, Rosario ; Juarranz Moratilla, Yasmina ; Lamana, Amalia ; Ocón, Elena ; Ortiz, Ana M. ; Gómez-León, Nieves ; González-Álvaro, Isidoro ; Pérez-Gomáriz, Rosa | Springer | 2015-02Spondyloarthritis (SpA) is a family of inflammatory diseases sharing clinical, genetic, and radiological features. While crucial for tailoring early interventions, validated prognostic biomarkers are scarce in SpA. We analyze the correlation bet[...]
