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Pérez García, Selene ; Carrión Caballo, Mar ; Gutiérrez-Cañas, Irene ; Villanueva-Romero, Raúl ; Castro Moreno, David ; Martínez, Carmen ; González-Álvaro, Isidoro ; Blanco, Francisco J. ; Juarranz Moratilla, Yasmina ; Gomáriz, Rosa P. | MDPI | 2019-12-22The extracellular matrix (ECM) is a complex and specialized three-dimensional macromolecular network, present in nearly all tissues, that also interacts with cell surface receptors on joint resident cells. Changes in the composition and physical[...]texto impreso
Pérez García, Selene ; Carrión Caballo, Mar ; Villanueva Romero, Raúl ; Hermida Gómez, Tamara ; Fernández Moreno, Mercedes ; Mellado, Mario ; Blanco, Francisco J. ; Juarranz Moratilla, Yasmina ; Gomáriz, Rosa P. | Wiley Open Acces | 2019Failure of therapeutic approaches for the treatment of osteoarthritis (OA) based on the inhibition of metalloproteinases, might be because of their constitutive expres? sion in homeostasis, together with their network complexity. The knowledge o[...]
