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Muñoz Sáez, Emma ; Munck García, Estefanía de ; Arahuetes Portero, Rosa María ; Vicente, Francisca ; Ortiz López, Francisco Javier ; Cantizani, Juan ; Gómez Miguel, Begoña | Elsevier | 2015-04-23Sphingosine-1-phosphate (S1P) is a bioactive lipid which regulates proliferation, cell migration, survival and differentiation by specific receptors activation. We studied its effects on L-BMAA treated neuroblastoma cells (SH-SY5Y), an amino aci[...]texto impreso
Fernández Acero, Teresa ; Rodríguez Escudero, Isabel ; Vicente, Francisca ; Monteiro, Maria Cândida ; Tormo, José R. ; Cantizani, Juan ; Molina, María ; Cid, Víctor J. | 2012-06-15The phosphatidylinositol 3-kinase (PI3K) pathway couples receptor-mediated signaling to essential cellular functions by generating the lipid second messenger phosphatidylinositol-3,4,5-trisphosphate. This pathway is implicated in multiple aspect[...]
