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López-Cortegano, Eugenio ; Vilas, Ana ; Caballero, Armando ; García-Dorado, Aurora | Wiley | 2016-08Inbreeding depression for ?tness traits is a key issue in evolutionary biology and conservation genetics. The magnitude ofinbreeding depression, though, may critically depend on the ef?ciency of genetic purging, the elimination or recessive dele[...]texto impreso
In conservation practice, preliminary assessments of extinction risk as well as emergency decisions are often based on scarce information. Thus, a simple 50/500 rule of thumb has been applied for a long time as a guidance to determine when genet[...]texto impreso
Bersabé García, Diego ; Caballero, Armando ; Pérez-Figueroa, Andrés ; García-Dorado, Aurora | Genetics Society of America | 2016-01Using computer simulation we explore the consequences of linkage on the inbreeding load of an equilibrium population, and on the efficiency of purging and the loss of genetic diversity after a reduction in population size. We find that linkage t[...]texto impreso
García-Dorado, Aurora ; Wuang, Jingliang ; López-Cortegano, Eugenio | Genetics Society of America | 2016-11The inbreeding depression of fitness traits can be a major threat to the survival of populations experiencing inbreeding. However, its accurate prediction requires taking into account the genetic purging induced by inbreeding, which can be achie[...]texto impreso
Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates suggest that its impact on individual fitness is even greater th[...]
