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Turdean-Ionescu, Claudia ; Stevensson, Baltzar ; Grins, Jekabs ; Izquierdo Barba, Isabel ; García, Ana ; Arcos Navarrete, Daniel ; Vallet Regí, María ; Eden, Mattias | Royal Society of Chemistry | 2015Silicate-based bioactive glasses exhibit bone-bonding properties due to the formation of a hydroxycarbonate apatite (HCA) layer at the glass surface on its contact with living tissues. This bone-healing process is triggered by ionic exchange bet[...]texto impreso
Martínez Carmona, Marina ; Izquierdo Barba, Isabel ; Colilla, Montserrat ; Vallet Regí, María | Elsevier | 2019-07-03The ability of bacteria to form biofilms hinders any conventional treatment for chronic infections and has serious socio-economic implications. For this purpose, a nanocarrier capable of overcoming the barrier of the mucopolysaccharide matrix of[...]texto impreso
Aguilar Colomer, Anna ; Colilla Nieto, Montserrat ; Izquierdo Barba, Isabel ; Jiménez Jiménez, Carla ; Mahillo, Ignacio ; Esteban, Jaime ; Vallet Regí, María | Elsevier | 2020-10-07Mesoporous silica nanoparticles (MSNs) are promising drug nanocarriers for infection treatment. Many investigations have focused on evaluating the capacity of MSNs to encapsulate antibiotics and release them in a controlled fashion. However, lit[...]texto impreso
Encinas, Noemí ; Angulo, Mercedes ; Astorga, Carlos ; Colilla, Montserrat ; Izquierdo Barba, Isabel ; Vallet Regí, María | Elsevier Science | 2018-12-05The design of drug delivery systems needs to consider biocompatibility and host body recognition for an adequate actuation. In this work, mesoporous silica nanoparticles (MSNs) surfaces were successfully modified with two silane molecules to pro[...]texto impreso
Pontremolli, Carlotta ; Izquierdo Barba, Isabel ; Montalbano, Giorgia ; Vallet Regí, María ; Vitale-Brovarone, Chiara ; Fiorilli, Sonia | Elsevier | 2019-12-14Hypothesis The treatment of bone fractures still represents a challenging clinical issue when complications due to impaired bone remodelling (i.e. osteoporosis) or infections occur. These clinical needs still require a radical improvement of the[...]texto impreso
Zwitterionization of biomaterials has been heightened to a potent tool to develop biocompatible materials able to inhibit bacterial and non-specific proteins adhesion. This constitutes a major progress in the biomedical field. This manuscript ov[...]
