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Pérez García, Selene ; Gutiérrez Cañas, Irene ; Seoane Valiño, Iria V. ; Fernández, Julián ; Mellado, Mario ; Leceta Martínez, Javier ; Tío, Laura ; Villanueva Romero, Raúl ; Juarranz Moratilla, Yasmina ; Pérez Gomáriz, Rosa María | 2016-09Current description of osteoarthritis includes the involvement of synovial inflammation. Studies contributing to understanding the mechanisms of cross-talk and feedback among the joint tissues could be relevant to the development of therapies th[...]texto impreso
Lamana, Amalia ; Villares, Ricardo ; Seoane Valiño, Iria V. ; Andrés, Nuria ; Lucas, Pilar ; Emery, Paul ; Vital, Edward M. ; Triguero-Martínez, Ana ; Márquez, Ana ; Ortiz, Ana M. ; Maxime, Robin ; Martínez, Carmen ; Martín, Javier ; Gomáriz, Rosa P. ; Ponchel, Frederique ; González-Álvaro, Isidoro ; Mellado, Mario | Frontiers Media | 2020-06-26Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show mode[...]texto impreso
Villanueva Romero, Raúl ; Gutiérrez Cañas, Irene ; Carrión Caballo, Mar ; Pérez García, Selene ; Seoane Valiño, Iria V. ; Martínez, Carmen ; Gomáriz, Rosa P. ; Juarranz Moratilla, Yasmina | Hindawi | 2018Genetic background, epigenetic modifications, and environmental factors trigger autoimmune response in rheumatoid arthritis (RA). Several pathogenic infections have been related to the onset of RA and may cause an inadequate immunological tolera[...]texto impreso
Seoane Valiño, Iria V. ; Martínez, Carmen ; Garcia-Vicuña, Rosario ; Ortiz, Ana M. ; Juarranz Moratilla, Yasmina ; Talayero, Vanessa C. ; González-Álvaro, Isidoro ; Gomáriz, Rosa P. ; Lamana, Amalia | Nature Publishing Group | 2018-02-01We previously reported that early arthritis (EA) patients with low vasoactive intestinal peptide (VIP) serum levels demonstrate a worse clinical disease course. In this study, we analysed whether variants in the VIP gene correlated with its seru[...]
