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Yadav, Monika ; Schiavone, Nicola ; Guzmán Aránguez, Ana Isabel ; Giansanti, Fabrizio ; Papucci, Laura ; Pérez de Lara, María Jesús ; Singh, Mandeep ; Kaur, Indu Pal | Springer Verlag | 2020-04-08Statins, widely prescribed for cardiovascular diseases, are also being eyed for management of age-related macular degeneration (AMD). Poor bioavailability and blood-aqueous barrier may however limit significant ocular concentration of statins fo[...]texto impreso
Yadav, Monika ; Guzmán Aránguez, Ana Isabel ; Pérez de Lara, María Jesús ; Singh, Mandeep ; Singh, Joga ; Kaur, Indu Pal | Elsevier | 2019-05-10Primary treatment for glaucoma relies on chronic instillation (daily) of intraocular pressure (IOP) lowering eye drops. Present study tends to develop and assess a novel sustained release bimatoprost loaded nanovesicular (BMT-NV) - thermosensit[...]texto impreso
Yadav, Monika ; Guzmán Aránguez, Ana Isabel ; Pérez de Lara, María Jesús ; Singh, Mandeep ; Singh, Joga ; Pal Kaur, Indu | Elsevier | 2019-08In vitro cytotoxicity and in vivo acute and 7 days repeat-dose ocular toxicity studies, were conducted in rabbits, in accordance with the Organisation for Economic Co-operation and Development (OECD) guidelines, for bimatoprost loaded nanovesicu[...]texto impreso
Singh, Mandeep ; Guzmán Aránguez, Ana Isabel ; Hussain, Afzal ; Srinivas, Cheerneni S. ; Kaur, Indu P. | Future Medicine | 2019-01-29Aim: Evaluation of solid lipid nanoparticles (SLNs) for ocular delivery of isoniazid (INH). Materials & methods: INH-SLNs were characterized for morphological, thermal, crystalline and nuclear magnetic resonance properties. In vitro release and [...]
