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Martínez Águila, Alejandro ; Fonseca Vázquez, Begoña ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | 2020-07-29Purpose: The objective of this study was to evaluate the changes in the melatoninergic receptors of DBA/2J and C57BL/6J mice with the development of glaucoma. DBA/2J mice are widely used to study the physiopathology of glaucoma due to the simila[...]texto impreso
Fonseca Vázquez, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Pintor, Jesús | Frontiers Media | 2017-10-10Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal mode[...]texto impreso
Peral Cerdá, Assumpta ; Martínez Águila, Alejandro ; Pastrana, Cristina ; Huete Toral, Fernando ; Carpena Torres, Carlos ; Carracedo Rodríguez, Juan Gonzalo | MDPI | 2020-07-27Glaucoma is an optical neuropathy associated to a progressive degeneration of retinal ganglion cells with visual field loss and is the main cause of irreversible blindness in the world. The treatment has the aim to reduce intraocular pressure. T[...]texto impreso
Fonseca, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Pintor, Jesús | Springer | 2016-11Glaucoma is a neurodegenerative disease that produces blindness. The main factor associated with this disease is an abnormally elevated intraocular pressure (IOP). To date, some attempts have been made to demonstrate the role of nucleotides modu[...]texto impreso
Guzmán Aránguez, Ana Isabel ; Fonseca, Begoña ; Carracedo Rodríguez, Juan Gonzalo ; Martín Gil, Alba ; Martínez Águila, Alejandro ; Pintor, Jesús | Contact Lens Association of Ophthalmologists | 2016-09Dry eye disease affects a substantial segment of the word population with increasing frequency. It is a multifactorial disease of the ocular surface and tear film, which causes ocular discomfort, visual disturbances, and tear instability with po[...]texto impreso
Martínez Águila, Alejandro ; Fonseca, Begoña ; Pérez de Lara, María Jesús ; Pintor Just, Jesús | American Society for Pharmacology and Experimental Therapeutics (ASPET) | 2016-05Melatonin is a neurohormone that is produced not only by the pineal gland but also by several ocular structures. One of the main physiologic roles of melatonin is the reduction of intraocular pressure (IOP). Using both control C57BL/6J and glauc[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Martínez Águila, Alejandro ; Rodríguez Pomar, Candela ; Bodas Romero, Julia ; Sánchez Naves, Juan ; Pintor, Jesús | Springer Verlag | 2019-10-24Purpose: To evaluate the effect of a new nutritional supplement based on melatonin on the intraocular pressure (IOP) in normotensive subjects. Patients and methods: A short-term prospective study was designed. Sixty-seven normotensive subjects w[...]texto impreso
Alkozi, Hanan Awad ; Sánchez Naves, Juan ; Pérez de Lara, María Jesús ; Carracedo Rodríguez, Juan Gonzalo ; Fonseca, Begoña ; Martínez Águila, Alejandro ; Pintor, Jesús | John Wiley & Sons Ltd. | 2016-09-06Purpose: To study the levels of melatonin in the aqueous humour of normotensive and hypertensive intraocular pressure (IOP) patients and to compare them to an animal model of glaucoma. Methods : A total of 37 eyes of 37 patients who underwent ca[...]texto impreso
El glaucoma es una neuropatía óptica progresiva crónica caracterizada por una degeneración de las células ganglionares retinianas y un daño a la cabeza del nervio óptico. De esta forma, hay una pérdida progresiva de campo visual que finalmente p[...]texto impreso
Martínez Águila, Alejandro ; Martín Gil, Alba ; Carpena Torres, Carlos ; Pastrana, Cristina ; Carracedo Rodríguez, Juan Gonzalo | MDPI | 2021-02-24Circadian rhythm and the molecules involved in it, such as melanopsin and melatonin, play an important role in the eye to regulate the homeostasis and even to treat some ocular conditions. As a result, many ocular pathologies like dry eye, corne[...]texto impreso
Huete Toral, Fernando ; Crooke, Almudena ; Martínez Águila, Alejandro ; Pintor, Jesús | Mary Ann Liebert | 2015-01-01Melatonin and its analog 5-MCA-NAT (5-methylcarboxyamino-N-acetyl tryptamine) are active compounds reducing intraocular pressure (IOP). This action is mediated through MT2 and the putative MT3 melatonin receptor, producing a transient reduction [...]texto impreso
Carpena Torres, Carlos ; Pintor, Jesús ; Pérez de Lara, María Jesús ; Toral, Fernando ; Crooke, Almudena ; Pastrana, Cristina ; Carracedo Rodríguez, Juan Gonzalo ; Cayuela López, Ana ; Sorzano Sánchez, Óscar ; Charbel, Carla ; Garzón Jiménez, Nuria ; Carballo Álvarez, Jesús ; Diz Arias, Elena ; Fernández Jiménez, Elena ; Peral Cerdá, Assumpta ; Gómez Pedrero, José Antonio ; Durán Prieto, Elena ; López Alonso, José Manuel ; Fernández Torres, Miguel Ángel ; Guzmán Aránguez, Ana Isabel ; Gómez Manzanares, Ángela ; Vázquez Moliní, Daniel ; Martínez Antón, Juan Carlos ; Bernárdez Vilaboa, Ricardo ; Mayorga Pinilla, Santiago ; Álvarez Fernández-Balbuena, Antonio ; Benítez, AntoJ. ; El Youssfi, Asmae Igalla ; León Álvarez, Alejandro ; Palomo Álvarez, Catalina ; LLedó Mayans, Victoria Eugenia ; Awad Alkozi, Hanan ; Sánchez Naves, Juan ; Martínez Alberquilla, Irene ; García Montero, María ; Ruiz Alcocer, Javier ; Madrid Costa, David ; Martínez Florentín, Gema ; Papas, Eric B. ; Medrano Muñoz, Sandra Milena ; Molina, Nancy ; Jurado, Sandra ; Oliveiros López, Juan ; Platero Alvarado, Nadiuska Cristine ; Garrido Mercado, Rafaela ; Pérez Garmendia, Carlos ; Antona Peñalba, Beatriz ; Barrio de Santos, Ana Rosa ; González Pérez, Mariano ; Pérez Garmendia, Carlos ; Serramito Blanco, María ; Privado Aroco, Ana ; Almalki, Wael ; Bodas Romero, Julia ; Ouzzani, Mohamed ; Paune, Jaume ; Calderón García, Raquel ; Pitarch Velasco, Aida ; Cebrián, José Luis ; Sánchez Pérez, Isabel ; García Rojo, Marta María ; Bonnin Arias, Cristina ; Sánchez Ramos, Celia ; Gutiérrez Jorrín, Sara Carmen ; Rodríguez Alonso, Xabier ; Laucirica Sáenz, Gorka ; Arranz Márquez, Esther ; Alonso Castellanos, Miriam ; Teus Guezala, Miguel Ángel ; Hernández Verdejo, José Luis ; Mármol Errasti, Esther ; Martín García, Beatriz ; Arriola Villalobos, Pedro ; Gómez de Liaño, Rosario ; Mínguez Caro, N ; Orduña Azcona, Javier ; Navarro Gil, Francisco Javier ; Huete Toral, Fernando ; Rodríguez Pomar, Candela ; Pastrana Robles, Cristina ; Martínez Águila, Alejandro ; Martín Gil, Alba ; Tomé de la Torre, Miguel Ángel | Facultad de Óptica y Optometría (UCM) | 2020Por cuarto año consecutivo los doctorandos de la Facultad de Óptica y Optometría de la Universidad Complutense de Madrid cuentan con un congreso propio organizado por y para ellos, el 4º PhDAY- FOO. Se trata de un congreso gratuito abierto en [...]texto impreso
Carpena Torres, Carlos ; Pintor, Jesús ; Huete Toral, Fernando ; Rodríguez Pomar, Candela ; Martínez Águila, Alejandro ; Carracedo Rodríguez, Juan Gonzalo | Taylor & Francis | 2020-07-07Purpose: To evaluate the preclinical efficacy of eye drops based on an extract of Artemia salina on the ocular surface of rabbits. Tear secretion, tear break-up time and corneal staining were measured. Material and methods: A preclinical and sho[...]
