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García Rincón, Daniel ; Díaz Alonso, Javier ; Paraíso Luna, Juan ; Otega, Zaira ; Aguareles, José ; Salas Quiroga, Adán de ; Jou, Cristina ; Prada, Inmaculada de ; Martínez Cerdeño, Verónica ; Aronica, Eleonora ; Guzmán, Manuel ; Pérez-Jiménez, María Ángeles ; Galve Roperh, Ismael | Frontiers Media | 2019-01Alterations of the PI3K/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway are causally involved in a subset of malformations of cortical development (MCDs) ranging from focal cortical dysplasia (FCD) to hemimegalencephaly an[...]texto impreso
Díaz Alonso, Javier ; Salas Quiroga, Adán de ; Paraíso Luna, Juan ; García Rincón, Daniel ; Garcez, Patricia P. ; Parsons, Maddy ; Andradas Arias, Clara | Oxford University Press | 2017-11Neuronal migration is a fundamental process of brain development, and its disruption underlies devastating neurodevelopmental disorders. The transcriptional programs governing this process are relatively well characterized. However, how environm[...]texto impreso
Aguareles, José ; Paraíso Luna, Juan ; Palomares, Belén ; Bajo-Grañeras, Raquel ; Navarrete, Carmen ; Ruiz-Calvo, Andrea ; García Rincón, Daniel ; García-Taboada, Elena ; Guzmán, Manuel ; Muñoz, Eduardo ; Galve Roperh, Ismael | BMC | 2019-03-08Background: The administration of certain cannabinoids provides neuroprotection in models of neurodegenerative diseases by acting through various cellular and molecular mechanisms. Many cannabinoid actions in the nervous system are mediated by C[...]texto impreso
The brain is the most complex organ in the body. Given the amount of information that it has to compute and integrate in behavioural and somatic responses, it comes as no surprise the enormous amount of different cells and circuit assemblies tha[...]
