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Autor Muñoz, Juan José |
Documentos disponibles escritos por este autor (4)
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Muñoz, Juan José ; García Ceca Hernández, Javier ; Montero Herradón, Sara ; Sánchez del Collado, Beatriz ; Alfaro Sánchez, David ; Zapata González, Agustín | Frontiers Media | 2018-04-03For a long time, the effects of distinct Eph tyrosine kinase receptors and their ligands, ephrins on the structure, immunophenotype, and development of thymus and their main cell components, thymocytes (T) and thymic epithelial cells (TECs), hav[...]texto impreso
García Ceca Hernández, Javier ; Alfaro Sánchez, David ; Montero Herradón, Sara ; Tobajas, Esther ; Muñoz, Juan José ; Zapata González, Agustín | Frontiers Media | 2015-06-26Numerous studies emphasize the relevance of thymocyte–thymic epithelial cell (TECs) interactions for the functional maturation of intrathymic T lymphocytes. The tyrosine kinase receptors, Ephs (erythropoietin-producing hepatocyte kinases) and th[...]texto impreso
Numerous epithelia undergo tubulogenesis and branching morphogenesis during their development (i.e., lung, salivary gland, pancreas) in order to establish sufficient available surface for their proper functioning. The thymus is a primary lymphoi[...]texto impreso
Muñoz, Juan José ; Tobajas, Esther ; Juara, Sonia ; Montero Herradón, Sara ; Zapata González, Agustín Gregorio | Springer | 2019-09-24The mechanisms that determine the commitment of thymic epithelial precursors to the two major thymic epithelial cell lineages, cTECs and mTECs, remain unknown. Here we show that FoxN1 nu mutation, which abolishes thymic epithelium differentiatio[...]