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Martínez Águila, Alejandro ; Fonseca Vázquez, Begoña ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | 2020-07-29Purpose: The objective of this study was to evaluate the changes in the melatoninergic receptors of DBA/2J and C57BL/6J mice with the development of glaucoma. DBA/2J mice are widely used to study the physiopathology of glaucoma due to the simila[...]texto impreso
Fonseca Vázquez, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Pintor, Jesús | Frontiers Media | 2017-10-10Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal mode[...]texto impreso
Pérez de Lara, María Jesús ; Guzmán Aránguez, Ana Isabel ; Gómez Villafuertes, María Rosa ; Gualix, Javier ; Miras Portugal, María Teresa ; Pintor, Jesús | Springer | 2018-06-08The pathogenesis of glaucoma involves numerous intracellular mechanisms including the purinergic system contribution. Furthermore, the presence and release of nucleotides and dinucleotides during the glaucomatous damage and the maintenance of de[...]texto impreso
Pérez de Lara, María Jesús ; Guzmán Aránguez, Ana Isabel ; Villa, Pedro, de la ; Díaz Hernández, Juan Ignacio ; Miras Portugal, María Teresa ; Pintor, Jesús | 2015-09-06Purpose: To study retinal extracellular ATP levels and to assess the changes in the vesicular nucleotide transporter (VNUT) expression in a murine model of glaucoma during the development of the disease. Methods: Retinas were obtained from glauc[...]
