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Olmeda Lozano, Bárbara ; García Álvarez, Begoña ; Gómez, Manuel J. ; Martínez Calle, Marta ; Cruz Rodríguez, Antonio ; Pérez Gil, Jesús | Federation of American Societies for Experimental Biology | 2017Surfactant protein B (SP-B), from the saposin-like family of proteins, is essential to facilitate the formation and proper performance of surface active films at the air-liquid interface of mammalian lungs, and lack of or deficiency in this prot[...]texto impreso
Olmeda Lozano, Bárbara ; García Álvarez, Begoña ; Gómez, M. J. ; Martínez Calle, Marta | Federation of American Societies for Experimental Biology (FASEB) | 2015Surfactant protein B (SP-B), from the saposin-like family of proteins, is essential to facilitate the formation and proper performance of surface active films at the air-liquid interface of mammalian lungs, and lack of or deficiency in this prot[...]texto impreso
Martínez Calle, Marta ; Alonso Eugenio, Alejandro ; Pérez-Gil, Jesús ; Olmeda Lozano, Bárbara | Elsevier | 2019-09Pulmonary surfactant is a lipid-protein complex which coats lung alveoli. It displays the essential function of reducing surface tension at the air-liquid interface, avoiding alveolar collapse during expiration. The optimized biophysical propert[...]texto impreso
Pulmonary surfactant is a lipid–protein complex that lines and stabilizes the respiratory interface in the alveoli, allowing for gas exchange during the breathing cycle. At the same time, surfactant constitutes the first line of lung defense aga[...]texto impreso
Martínez Calle, Marta ; Prieto, Manuel ; Olmedo, Barbara ; Fedorov, Aleksander ; Loura, Luís M.S. ; Pérez Gil, Jesús | Elsevier | 2020-02-15Surfactant protein SP-B is absolutely required for the generation of functional pulmonary surfactant, a unique network of multilayered membranes, which stabilizes the respiratory air-liquid interface. It has been proposed that SP-B assembles int[...]texto impreso
El sistema respiratorio es imprescindible para la obtención del oxígeno necesario para los procesos metabólicos. El intercambio gaseoso tiene lugar a través de la barrera alveolo-capilar, donde el oxígeno y el dióxido de carbono difunden entre e[...]
