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Román González, Elvira ; Coman, Ioana V ; Prieto, Daniel ; Alonso Monge, Rebeca ; Pla Alonso, Jesús | American Society for Microbiology | 2019-02-13Clustered regularly interspaced short palindromic repeat (CRISPR) methodology is not only an efficient tool in gene editing but also an attractive platform to facilitate DNA, RNA, and protein interactions. We describe here the implementation of [...]texto impreso
Morales-Menchén, Ana ; Navarro García, Federico ; Guirao-Abad, José P ; Román González, Elvira ; Prieto, Daniel ; Coman, Ioana V ; Pla Alonso, Jesús ; Alonso Monge, Rebeca | 2018-05-03Certain yeasts secrete peptides known as killer toxins or mycocins with a deleterious effect on sensitive yeasts or filamentous fungi, a common phenomenon in environmental species. In a recent work, different () strains isolated from a wide var[...]texto impreso
Navarro García, Federico ; Pla Alonso, Jesús ; Alonso Monge, Rebeca ; Román González, Elvira | 2015-02-20Se ha evaluado la utilización de una aplicación gratuita disponible en internet para teléfonos inteligentes (Socrative) con los objetivos de a) motivación y mejora del aprendizaje del alumnado, y b)obtención de retroalimentación para mejorar la [...]texto impreso
Román, Elvira ; Correia, C. Inês Ribeiro ; Prieto, Daniel ; Alonso Monge, Rebeca ; Pla Alonso, Jesús | Springer Verlag | 2019-03-14In 1993, Brewster and Gustin described the existence of a kinase whose activity was essential for Saccharomyces cerevisiae to grow in environments with high osmolarity. This led to the discovery of the HOG pathway, a MAP kinase (MAPK) pathway th[...]texto impreso
Different signal transduction pathways mediated by MAP kinases have been described in Candida albicans. These pathways sense different stimuli and, therefore, elaborate specific responses. Hog1 was identified as the MAPK that is primarily involv[...]texto impreso
Román González, Elvira ; Alonso Monge, Rebeca ; Miranda, Alberto ; Pla Alonso, Jesús | Public Library of Science | 2015-07-21The cell wall integrity pathway (CWI) plays an important role in the biogenesis of the cell wall in Candida albicans and other fungi. In the present work, the C. albicans MKK2 gene that encodes the putative MAPKK of this pathway was deleted in d[...]texto impreso
Urrialde, Verónica ; Prieto, Daniel ; Pla Alonso, Jesús ; Alonso Monge, Rebeca | Frontiers | 2015-02-11Arsenate (As (V)) is the dominant form of the toxic metalloid arsenic (As). Microorganisms have consequently developed mechanisms to detoxify and tolerate this kind of compounds. In the present work, we have explored the arsenate sensing and sig[...]texto impreso
Herrero de Dios, Carmen María ; Román García, Elvira ; Diez, Carla ; Alonso Monge, Rebeca ; Pla Alonso, Jesús | Elsevier | 2013-01MAPK pathways are conserved and complex mechanisms of signaling in eukaryotic cells. These pathways mediate adaptation to different stress conditions by a core kinase cascade that perceives changes in the environment by different upstream elemen[...]
