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Gamo, Ana M. ; Gónzalez-Vera, Juan A. ; Rueda-Zubiaurre, Ainoa ; Alonso, Dulce ; Vázquez-Villa, Henar ; Martín-Couce, Lidia ; Palomares, Oscar ; López, Juan A. ; Martín-Fontecha, Mar ; Benhamú, Bellinda ; López-Rodríguez, María L. ; Ortega-Gutiérrez, Silvia | Wiley | 2015Determination of the targets of a compound remains an essential aspect in drug discovery. A complete understanding of all binding interactions is critical to recognize in advance both therapeutic effects and undesired consequences. However, the[...]texto impreso
Martínez Santos, Paula, Paula ; Baldán Martín, Montserrat ; López, Juan A. ; Martín Lorenzo, Marta ; Santiago Hernández, Aránzazu ; Agudieza, Marta ; Cabrera Sierra, Martha ; Calvo, Eva ; Vázquez, Jesús ; Ruiz Hurtado, Gema ; Vivanco, Fernando ; Ruilope, Luis M ; Barderas, María G. ; Alvarez-Llamas, Gloria | Elsevier | 2019-03Background and aims The predictive value of traditional CV risk calculators is limited. Novel indicators of CVD progression are needed particularly in the young population. The main aim of this study was the identification of a molecular profile[...]texto impreso
Martín Lorenzo, Marta ; Martínez, Paula J. ; Baldán Martín, Montserrat ; López, Juan A. ; Mínguez, Pablo ; Santiago Hernández, Aránzazu ; Vázquez, Jesús ; Segura, Julián ; Ruiz Hurtado, Gema ; Vivanco, Fernando ; Barderas, María G. ; Ruilope, Luis M ; Alvarez-Llamas, Gloria | American Heart Association | 2019-02-04Resistant hypertension prevalence is progressively increasing, and prolonged exposure to suboptimal blood pressure control results in higher cardiovascular risk and end-organ damage. Among various antihypertensive agents, spironolactone seems th[...]
