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Paris, Juan L. ; Torre, Paz de la ; Manzano, Miguel ; Cabanas, Victoria M. ; Flores, Ana I. ; Vallet Regí, María | Elsevier | 2016-03-15The potential use of human Decidua-derived mesenchymal stem cells (DMSCs) as a platform to carry mesoporous silica nanoparticles in cancer therapy has been investigated. Two types of nanoparticles were evaluated. The nanoparticles showed negligi[...]texto impreso
De la Torre, Paz ; Paris, J. L. ; Fernández de la Torre, Miguel ; Vallet Regí, María ; Flores, Ana I. | MDPI | 2021-02-10Combination therapies constitute a powerful tool for cancer treatment. By combining drugs with different mechanisms of action, the limitations of each individual agent can be overcome, while increasing therapeutic benefit. Here, we propose emplo[...]texto impreso
Serrano, Luis J. ; Cañete, Ana ; García Leal, Tamara ; Tomás Gallardo, Laura ; Flores, Ana I. ; Torre, Paz de la ; Liras, Antonio ; Sánchez, María José | Thieme Publishing | 2018-08The development of new strategies based on cell therapy approaches to correct haemophilia A (HA) requires further insights into new cell populations capable of producing coagulation factor VIII (FVIII) and presenting stable engraftment potential[...]texto impreso
Paris, J.L. ; Torre, Paz de la ; Cabañas Criado, Victoria ; Manzano García, Miguel ; Flores, Ana I. ; Vallet Regí, María | Elsevier Science BV | 2018-11-07A Trojan-horse strategy for cancer therapy employing tumor-tropic mesenchymal stem cells transfected with a non-viral nanovector is here presented. In this sense, ultrasound-responsive mesoporous silica nanoparticles were coated with a polycatio[...]texto impreso
Paris, J.L. ; Torre, Paz de la ; Cabañas Criado, Victoria ; Manzano García, Miguel ; Grau, Montserrat ; Flores, Ana I. ; Vallet Regí, María | Royal Society of Chemistry | 2017-05-07A new platform constituted by engineered responsive nanoparticles transported by human mesenchymal stem cells is here presented as a proof of concept. Ultrasound-responsive mesoporous silica nanoparticles are coated with polyethylenimine to favo[...]
