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Cacho, Isabel ; Sánchez Naves, Juan ; Batres Valderas, Laura ; Carracedo Rodríguez, Juan Gonzalo ; Pintor Just, Jesús | Hindawi Publishing Corporation | 2015Purpose. To compare the intraocular pressure (IOP) before and after Laser In Situ Keratomileusis (LASIK), measured by Diaton, Perkins, and noncontact air pulse tonometers. Methods. Fifty-seven patients with a mean age of 34.88 were scheduled for[...]texto impreso
Dry eye syndrome is a common disorder provoking changes in tear quantity and composition being the most common ophthalmic manifestation of systemic inflammatory diseases. Untreated dry eye could cause increased risk of ocular infection, corneal[...]texto impreso
Martínez Águila, Alejandro ; Fonseca, Begoña ; Pérez de Lara, María Jesús ; Pintor Just, Jesús | American Society for Pharmacology and Experimental Therapeutics (ASPET) | 2016-05Melatonin is a neurohormone that is produced not only by the pineal gland but also by several ocular structures. One of the main physiologic roles of melatonin is the reduction of intraocular pressure (IOP). Using both control C57BL/6J and glauc[...]texto impreso
The recent discovery of the photoreceptor melanopsin in lens epithelial cells has opened the possibility of modulating this protein by light stimulation. Experiments carried out on New Zealand white rabbits have demonstrated that the release of [...]texto impreso
Jacob, Tali Fishman ; Singh, Vijay ; Dixit, Mudit ; Ginsburg-Shmuel, Tamar ; Fonseca Vázquez, Begoña ; Pintor Just, Jesús ; Youdim, Moussa B. H. ; Major, Dan T. ; Weinreb, Orly ; Fischer, Bilha | Springer Verlag | 2018-09Extracellular nucleotides can regulate the production/drainage of the aqueous humor via activation of P2 receptors, thus affecting the intraocular pressure (IOP). We evaluated 5-OMe-UDP(?-B), 1A, a potent P2Y6-receptor agonist, for reducing IOP [...]texto impreso
LLedó Mayans, Victoria Eugenia ; Alkozi, Hanan Awad ; Pintor Just, Jesús | Taylor & Francis | 2019-01-24Purpose: Melatonin is a neurohormone mainly synthesized in the pineal gland; however, it is also present in the aqueous humor. One of melatonins’ functions in the eye is the regulation of intraocular pressure (IOP). Melatonin is known to be sens[...]
