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Bravo Osuna, Irene ; Andrés-Guerrero, Vanessa ; Arranz-Romera, Alicia ; Esteban Pérez, Sergio ; Molina-Martínez, Irene T. ; Herrero-Vanrell, Rocio | Elsevier | 2018-02-15Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These diseases include age-related macular degeneration (AMD), diabetic Retinopathy (DR) and glaucoma, among others. Also, there are genetic disorders[...]texto impreso
Arranz Romera, Alicia ; Davis, Benjamin M. ; Bravo Osuna, Irene ; Esteban Pérez, Sergio ; Molina-Martínez, Irene T. ; Shamsher, Ehtesham ; Ravindran, Nivedita ; Guo, Li ; Cordeiro, M. Francesca ; Herrero-Vanrell, Rocio | Elsevier | 2019-03-10Glaucoma is a multifactorial neurodegenerative disorder and one of the leading causes of irreversible blindness globally and for which intraocular pressure is the only modifiable risk factor. Although neuroprotective therapies have been suggeste[...]texto impreso
Zhao, Min ; Rodríguez Villagra, Esther ; Kowalczuk, Laura ; Le Normand, Manon ; Berdugo, Marianne ; Levy-Boukris, Rinath ; El Zaoui, Ikram ; Kaufmann, Béatrice ; Gurny, Robert ; Bravo-Osuna, Irene ; Molina-Martínez, Irene T. ; Herrero-Vanrell, Rocio ; Behar-Cohen, Francine | Elsevier | 2017-11-28Mineralocorticoid receptor (MR)contributes to retinal/choroidal homeostasis. Excess MR activation has been shown to be involved in pathogenesis of central serous chorioretinopathy (CSCR). Systemic administration of MR antagonist (MRA) reduces su[...]texto impreso
Esteban Pérez, Sergio ; Bravo Osuna, Irene ; Andrés-Guerrero, Vanessa ; Molina-Martínez, Irene T. ; Herrero-Vanrell, Rocio | Bentham Science | 2019-09-05The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to bi[...]
