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Villalba, Mayte ; Barderas, R. ; Mas, S. ; Colás, S. ; Batanero, E. ; Rodríguez García, Rosalía | Esmon Publicidad | 2014The Amaranthaceae family is composed of about 180 genera and 2500 species. These common weeds have become increasingly relevant as triggers of allergy in the last few years, as they are able to rapidly colonize salty and arid soils in extensive [...]texto impreso
Torres, María ; Palomares, Oscar ; Quiralte, Joaquín ; Pauli, Gabrielle ; Rodríguez García, Rosalía ; Villalba, Mayte | PLOS | 2015-07Endo-?-1,3-glucanases are widespread enzymes with glycosyl hydrolitic activity involved in carbohydrate remodelling during the germination and pollen tube growth. Although members of this protein family with allergenic activity have been reporte[...]texto impreso
Oeo-Santos, Carmen ; López Rodríguez, Juan C. ; García-Mouton, Cristina ; San Segundo-Acosta, Pablo ; Jurado, Aurora ; Moreno-Aguilar, Carmen ; García-Álvarez, Begoña ; Pérez Gil, Jesús ; Villalba, Mayte ; Barderas Manchado, Rodrigo ; Cruz Rodríguez, Antonio | Elsevier | 2020-03-04Ole e 7 allergen from Olea europaea pollen possesses a major clinical relevance because it produces severe symptoms, such as anaphylaxis, in allergic patients exposed to high olive pollen counts. Ole e 7 is a non-specific lipid transfer protein [...]texto impreso
Over the past few decades, significant scientific progress has influenced clinical allergy practice. The biological standardization of extracts was followed by the massive identification and characterization of new allergens and their progressiv[...]texto impreso
Lázaro Gorines, Rodrigo ; López Rodríguez, Juan Carlos ; Benedé, Sara ; González, Miguel ; Mayorga, Cristobalina ; Vogel, Lothar ; Martínez del Pozo, Álvaro ; Lacadena, Javier ; Villalba, Mayte | Nature Research | 2020-07-23Immunotoxins appear as promising therapeutic molecules, alternative to allergen-specifcimmunotherapy. In this work, we achieved the development of a protein chimera able to promote specifc cell death on efector cells involved in the allergic rea[...]texto impreso
Sirvent, Sofía ; Cantó, Belén ; Gómez, Francisca ; Blanca, Natalia ; Cuesta-Herranz, Javier ; Canto, Gabriela ; Blanca, Miguel ; Rodíguez, Rosalía ; Villalba, Mayte ; Palomares, Oscar | John Wiley & Sons Ltd | 2014Background:Act d 12 (11S globulin) and Act d 13 (2S albumin) are two novel relevant allergens from kiwi seeds that might be useful to improve the diagnostic sensitivity and the management of kiwifruit-allergic patients. Objective:To perform a co[...]texto impreso
García-Blanca, A. ; Aranda, A. ; Blanca-Lopez, N. ; Pérez, D. ; Gómez, F. ; Mayorga, C. ; Torres, M.J. ; Díaz-Perales, A. ; Perkins, J.R. ; Villalba, Mayte ; Blanca, M. ; Canto, G. | Wiley-Blacwell | 2015-09Background: Peanut allergens are common responsible of food allergy. Analyses of sensitization patterns, relationships with other allergens, clinical symptoms and variation with age are needed. We studied sensitization to Ara h 2, Ara h 9 and Pr[...]texto impreso
Prado, Noela ; De Dios Alche, Juan ; Casado-Vela, Juan ; Mas, Salvador ; Villalba, Mayte ; Rodríguez, Rosalía ; Batanero, Eva | Elsevier | 2014-03texto impreso
Alvarez-Llamas, Gloria ; Maes, Xavier ; Muñoz-García, Esther ; Villalba, Mayte ; Rodríguez, Rosalía ; Pérez-Gordo, Marina ; Vivanco, Fernando ; Pérez-Gordo, Carlos ; Cuesta-Herranz, Javier | Elsevier | 2015-03Mustard is a condiment added to a variety of foodstuffs and a frequent cause of food allergy. A new strategy for the detection of mustard allergen in food products is presented. The methodology is based on liquid chromatography analysis coupled [...]texto impreso
Mas García, Salvador ; Boissy, Patrice ; Monsalve, Rafael I. ; Cuesta-Herranz, Javier ; Díaz-Perales, Araceli ; Colás, Carlos ; Rodríguez, Rosalía ; Barderas, Rodrigo ; Villalba, Mayte | Karger | 2015Amaranthaceae pollen allergy incidence has increased in the last years due to the desertification process occurring in many countries. In some regions of Spain,Salsola kali is the main cause of pollinosis at almost the same level than olive and [...]texto impreso
Castro, L. ; Mas, S. ; Bardenas, R. ; Colás, C. ; García-Sellés, J. ; Barber, D. ; Rodríguez, R. ; Villalba, Mayte | Karger | 2014-02Salsola kali is an Amaranthaceae weed with important repercussions for pollinosis in temperate areas. Ole e 1-like members are relevant allergens in pollen from different species. We aimed to characterize and produce as recombinant allergen S. k[...]texto impreso
Pastor-Vargas, C. ; Maroto, A.S. ; Díaz-Perales, A. ; Villalba, Mayte ; Casillas Díaz, N. ; Vivanco, F. ; Cuesta-Herranz, J. | John Wiley & Sons Ltd | 2015Food allergy is recognized as a major public health issue, especially in early childhood. It has been hypothesized that early sensitization to food allergens maybe due to their ingestion as components dissolved in the milk during the breastfeedi[...]texto impreso
López-Rodríguez, Juan C. ; Barderas Manchado, Rodrigo ; Echaide Torreguitar, Mercedes ; Pérez Gil, Jesús ; Villalba, Mayte ; Batanero Cremades, Eva ; Cruz Rodríguez, Antonio | American Chemical Society | 2016-10-25Aeroallergens are airborne substances?mainly proteins?capable of triggering Th2-immune responses in respiratory allergies. They enter into the body through the upper airways, reaching the mucosa afterward. Mucosae lining at the luminal side cons[...]texto impreso
Ole e 9 and Fra e 9 are two allergenic ?-1,3-glucanases from olive and ash tree pollens, respectively. Both proteins present a modular structure with a catalytic N-terminal domain and a carbohydrate-binding module (CBM) at the C-terminus. Despit[...]texto impreso
Sirvent, Sofía ; Cantó, Belén ; Cuesta-Herranz, Javier ; Gómez, Francisca ; Canto, Gabriela ; Blanca, Natalia ; Rodríguez, Rosalía ; Villalba, Mayte ; Palomares, Oscar | Elsevier | 2014Background: Kiwifruit is a common cause of IgE-mediated food allergy. Component-resolved diagnosis of kiwifruit allergy suggests that relevant allergenic components are still undiscovered. The presence of allergens in kiwi seeds has not been inv[...]
