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La presente tesis doctoral que lleva por título “Alteraciones oculares embrionarias por déficit dietario materno de ácido fólico: análisis de imagen, caracterización óptica y biológica” aborda el estudio óptico y biológico de tejidos oculares de[...]texto impreso
Sijilmassi, Ouafa ; López Alonso, José Manuel ; Rio Sevilla, Aurora del ; Murillo González, Jorge Alfonso ; Barrio Asensio, María del Carmen | Taylor & Francis | 2018-11Purpose: Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins its development fro[...]texto impreso
Sijilmassi, Ouafa ; López Alonso, José Manuel ; Barrio Asensio, María del Carmen ; Río Sevilla, Aurora, del | Wiley | 2018-08Immunohistochemistry section staining is not always easy to interpret. Manual quantification of immunohistochemical staining is limited by the observer visual ability to detect changes in level staining. Hence, the quantification of immunostaini[...]texto impreso
Sijilmassi, Ouafa ; López Alonso, José Manuel ; Río Sevilla, Aurora, del ; Barrio Asensio, María del Carmen | Wiley?VCH Verlag GmbH | 2020-09-27The present article describes the development of a technique, applied to paraffin?embedded tissues, which uses three different wavelengths of monochromatic light (?1 = 445?nm, ?2 = 540?nm and ?3 = 660?nm) for the measures of the degree of polari[...]texto impreso
Sijilmassi, Ouafa ; López Alonso, José Manuel ; Río Sevilla, Aurora, del ; Barrio Asensio, María del Carmen | Elsevier | 2020-05-30The purpose of this study was to investigate effects of low maternal folic acid (FA) status on many eye structures in embryonic mice using multifractal analysis, a method for describing complex structural patterns. To do this, we used the FracLa[...]texto impreso
Sijilmassi, Ouafa ; López Alonso, José Manuel ; Río Sevilla, Aurora, del ; Barrio Asensio, María del Carmen | Elsevier | 2020-05-30The aim of this work is to study local changes of fractality in mouse embryonic lens. Embryos were removed from female mice that have been subjected to a diet deficient in folic acid for two and eight weeks. The local change of fractality is stu[...]
