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Nevzorova, Yulia A. ; Boyer-Diaz, Zoe ; Cubero, Francisco Javier ; Gracia Sancho, Jordi | Elsevier | 2020-04-21Animal models are crucial for improving our understanding of human pathogenesis, enabling researchers to identify therapeutic targets and test novel drugs. In the current review, we provide a comprehensive summary of the most widely used experim[...]texto impreso
Benedé-Ubieto, Raquel ; Estévez-Vázquez, Olga ; Cubero, Francisco Javier ; Nevzorova, Yulia A. | Dove Medical Press | 2020-02-18The epidemic of the century, Diabetes Mellitus (DM) is continuously rising. Intensive research is urgently needed whereby experimental models represent an essential tool to optimise the diagnostic strategy and to improve therapy. In this review,[...]texto impreso
Tomás-Loba, Antonia ; Manieri, Elisa ; González-Terán, Bárbara ; Mora, Alfonso ; Leiva-Vega, Luis ; Santamans, Ayelén M. ; Romero-Becerra, Rafael ; Rodríguez, Elena ; Pintor-Chocano, Aránzazu ; Feixas, Ferran ; López, Juan Antonio ; Caballero, Beatriz ; Trakala, Marianna ; Blanco, Óscar ; Torres, Jorge L. ; Hernández-Cosido, Lourdes ; Montalvo-Romeral, Valle ; Matesanz, Nuria ; Roche-Molina, Marta ; Bernal, Juan Antonio ; Mischo, Hannah ; León, Marta ; Caballero, Ainoa ; Miranda-Saavedra, Diego ; Ruiz-Cabello, Jesús ; Nevzorova, Yulia A. ; Cubero, Francisco Javier ; Bravo, Jerónima ; Vázquez, Jesús ; Malumbres, Marcos ; Marcos, Miguel ; Osuna, Silvia ; Sabio, Guadalupe | Nature Research | 2019-04-10The cell cycle is a tightly regulated process that is controlled by the conserved cyclin-dependent kinase (CDK)–cyclin protein complex1. However, control of the G0-to-G1 transition is not completely understood. Here we demonstrate that p38 MAPK [...]texto impreso
Hübbers, Anna ; Hennings, Julia ; Lambertz, Daniela ; Haas, Ute ; Trautwein, Christian ; Nevzorova, Yulia A. ; Sonntag, Roland ; Liedtke, Christian | MDPI | 2020-05-05Liver fibrosis is a wound healing process in response to chronic liver injury, which is characterized by the accumulation of extracellular collagen produced by Hepatic Stellate Cells (HSCs). This process involves cell cycle re-entry and prolifer[...]texto impreso
Torres, Sandra ; Abdullah, Zeinab ; Brol, Maximilian J. ; Hellerbrand, Claus ; Fernández, Mercedes ; Fiorotto, Romina ; Klein, Sabine ; Königshofer, Philipp ; Liedtke, Christian ; Lotersztajn, Sophie ; Nevzorova, Yulia A. ; Schierwagen, Robert ; Reiberger, Thomas ; Uschner, Frank Erhard ; Tacke, Frank ; Weiskirchen, Ralf ; Trebicka, Jonel | MDPI | 2020-03-16Molecular and cellular research modalities for the study of liver pathologies have been tremendously improved over the recent decades. Advanced technologies offer novel opportunities to establish cell isolation techniques with excellent purity, [...]
