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Differential effect of membrane composition on the pore-forming ability of four fifferent sea Anemone Actinoporins

García-Linares, Sara ; Rivera de la Torre, Esperanza ; Morante, Koldo ; Tsumoto, Kouhei ; Caaveiro, José M. M. ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | American Chemical Society | 2016-11

Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins (PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII, respectively), produced by three different sea anemone specie[...]

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The Effect of Cholesterol on the Long-Range Network of Interactions Established among Sea Anemone Sticholysin II Residues at the Water-Membrane Interface

García-Linares, Sara ; Alm, Ida ; Maula, Terhi ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | MDPI | 2015

Actinoporins are ?-pore forming proteins with therapeutic potential, produced by sea anemones. Sticholysin II (StnII) from Stichodactyla helianthus is one of its most extensively characterized members. These proteins remain stably folded in wate[...]

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