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American Society for Clinical Investigation |
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Rosas-Aguirre, A. ; Patra, K.P. ; Calderón, M. ; Torres, K. ; Gamboa, D. ; Arocutipa, E. ; Málaga, E. ; Garro, K. ; Fernández, C. ; Trompeter, G. ; Alnasser, Y. ; Llanos-Cuentas, A. ; Gilman, R.H. ; Vinetz, J.M. | American Society for Clinical Investigation | 2020-12-14T16:10:08ZBACKGROUND. Serological tools for the accurate detection of recent malaria exposure are needed to guide and monitor malaria control efforts. IgG responses against Plasmodium vivax and P. falciparum merozoite surface protein-10 (MSP10) were measu[...]texto impreso
Yang, Hailin ; Kim, Sung-Kwon ; Kim, Mikyung ; Reche, Pedro A ; Morehead, Tiara J ; Damon, Inger K ; Welsh, Raymond M ; Reinherz, Ellis L | American Society for Clinical Investigation | 2005The EGF-like domain of smallpox growth factor (SPGF) targets human ErbB-1, inducing tyrosine phosphorylation of certain host cellular substrates via activation of the receptor's kinase domain and thereby facilitating viral replication. Given the[...]texto impreso
Garay-Baquero, D.J. ; White, C.H. ; Walker, N.F. ; Tebruegge, M. ; Schiff, H.F. ; Ugarte-Gil, C. ; Morris-Jones, S. ; Marshall, B.G. ; Manousopoulou, A. ; Adamson, J. ; Vallejo, A.F. ; Bielecka, M.K. ; Wilkinson, R.J. ; Tezera, L.B. ; Woelk, C.H. ; Garbis, S.D. ; Elkington, P. | American Society for Clinical Investigation | 2020-12-14T16:06:24ZBACKGROUND. Tuberculosis (TB) kills more people than any other infection, and new diagnostic tests to identify active cases are required. We aimed to discover and verify novel markers for TB in nondepleted plasma. METHODS. We applied an optimize[...]texto impreso
Broger, T. ; Nicol, M.P. ; Sigal, G.B. ; Gotuzzo, E. ; Zimmer, A.J. ; Surtie, S. ; Caceres-Nakiche, T. ; Mantsoki, A. ; Reipold, E.I. ; Székely, R. ; Tsionsky, M. ; van Heerden, J. ; Plisova, T. ; Chikamatsu, K. ; Lowary, T.L. ; Pinter, A. ; Mitarai, S. ; Moreau, E. ; Schumacher, S.G. ; Denkinger, C.M. | American Society for Clinical Investigation | 2020-12-14T16:06:09ZBACKGROUND. Inadequate tuberculosis (TB) diagnostics are a major hurdle in the reduction of disease burden, and accurate point-of-care tests (POCTs) are urgently needed. We assessed the diagnostic accuracy of Fujifilm SILVAMP TB lipoarabinomanna[...]texto impreso
Dey, Soumyadeep ; Cui, Zhenzhong ; Gavrilova, Oksana ; Zhang, Xiaojie ; Gassmann, Max ; Noguchi, Constance T. | American Society for Clinical Investigation | 2020-07-14T00:01:08ZThe blood hormone erythropoietin (EPO), upon binding to its receptor (EpoR), modulates high-fat diet-induced (HFO-induced) obesity in mice, improves glucose tolerance, and prevents white adipose tissue inflammation. Transgenic mice with constitu[...]