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Methodologies to generate, extract, purify and fractionate yeast ECM for analytical use in proteomics and glycomics.

Faria Oliveira, Fábio ; Carvalho, Joana ; Belmiro, Celso LR ; Martinez Gomariz, Montserrat ; Hernaez, Maria Luisa ; Pavão, Mauro ; Gil, Concha ; Lucas, Cândida ; Ferreira, Célia | BioMed Central | 2014

BACKGROUND In a multicellular organism, the extracellular matrix (ECM) provides a cell-supporting scaffold and helps maintaining the biophysical integrity of tissues and organs. At the same time it plays crucial roles in cellular communication [...]

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Sub-proteomic study on macrophage response to Candida albicans unravels new proteins involved in the host defense against the fungus.

Reales Calderón, José Antonio ; Martínez Solano, Laura ; Martinez Gomariz, Montserrat ; Nombela, César ; Molero, Gloria ; Gil, Concha | Elsevier | 2012-08

In previous proteomic studies on the response of murine macrophages against Candida albicans, many differentially expressed proteins involved in processes like inflammation, cytoskeletal rearrangement, stress response and metabolism were identif[...]

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