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García Rincón, Daniel ; Díaz Alonso, Javier ; Paraíso Luna, Juan ; Otega, Zaira ; Aguareles, José ; Salas Quiroga, Adán de ; Jou, Cristina ; Prada, Inmaculada de ; Martínez Cerdeño, Verónica ; Aronica, Eleonora ; Guzmán, Manuel ; Pérez-Jiménez, María Ángeles ; Galve Roperh, Ismael | Frontiers Media | 2019-01Alterations of the PI3K/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway are causally involved in a subset of malformations of cortical development (MCDs) ranging from focal cortical dysplasia (FCD) to hemimegalencephaly an[...]texto impreso
Salas Quiroga, Adán de ; García-Rincón, Daniel ; Gómez-Domínguez, Daniel ; Valero, Manuel ; Simón-Sánchez, Samuel ; Paraíso-Luna, Juan ; Aguareles, José ; Pujadas, Mitona ; Muguruza, Carolina ; Callado, Luis F. ; Lutz, Beat ; Guzmán, Manuel ; Menéndez de la Prida, Liset ; Galve-Roperh, Manuel | Springer Nature | 2020-01-26Prenatal exposure to ?9 -tetrahydrocannabinol (THC), the most prominent active constituent of cannabis, alters neurodevelopmental plasticity with a long-term functional impact on adult offspring. Specifically, THC affects the development of pyra[...]texto impreso
Aguareles, José ; Paraíso Luna, Juan ; Palomares, Belén ; Bajo-Grañeras, Raquel ; Navarrete, Carmen ; Ruiz-Calvo, Andrea ; García Rincón, Daniel ; García-Taboada, Elena ; Guzmán, Manuel ; Muñoz, Eduardo ; Galve Roperh, Ismael | BMC | 2019-03-08Background: The administration of certain cannabinoids provides neuroprotection in models of neurodegenerative diseases by acting through various cellular and molecular mechanisms. Many cannabinoid actions in the nervous system are mediated by C[...]
