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Blanco Imperiali, Ayelén M. ; Gómez Boronat, Miguel ; Alonso Gómez, Ángel Luis ; Yufa, Roman ; Unniappan, Suraj ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel | Public Library of Science | 2017-02-08Ghrelin is the only known hormone posttranslationally modified with an acylation. This modification is crucial for most of ghrelin’s physiological effects and is catalyzed by the polytopic enzyme ghrelin O-acyltransferase (GOAT). The aim of this[...]texto impreso
Blanco Imperiali, Ayelén M. ; Bertucci, Juan I. ; Ramesh, Naresh ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel ; Unniappan, Suraj | Springer Nature | 2017-03-24Glucose homeostasis is an important biological process that involves a variety of regulatory mechanisms. This study aimed to determine whether ghrelin, a multifunctional gut-brain hormone, modulates intestinal glucose transport in goldfish (Cara[...]texto impreso
Blanco Imperiali, Ayelén M. ; Bertucci, Juan I. ; Sánchez Bretaño, Aída ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel ; Unniappan, Suraj | Elsevier | 2017-02-15Ghrelin, a multifunctional gut-brain hormone, is involved in the regulation of gastric functions in mammals. This study aimed to determine whether ghrelin modulates digestive enzymes in goldfish (Carassius auratus). Immunofluorescence microscopy[...]texto impreso
Blanco Imperiali, Ayelén M. ; Bertucci, Juan I. ; Valenciano González, Ana Isabel ; Delgado, María Jesús ; Unniappan, Suraj | Elsevier | 2017-07Ghrelin is an important gut-derived hormone with an appetite stimulatory role, while most of the intestinal hormones, including cholecystokinin (CCK), peptide YY (PYY) and glucagon-like peptide-1 (GLP-1), are appetite-inhibitors. Whether these i[...]texto impreso
Sánchez Bretaño, Aída ; Blanco Imperiali, Ayelén M. ; Unniappan, Suraj ; Kah, Olivier ; Gueguen, Marie-M. ; Bertucci, Juan I. ; Alonso Gómez, Ángel Luis ; Valenciano González, Ana Isabel ; Isorna Alonso, Esther ; Delgado, María J. | Public Library of Sciences (PLOS) | 2015-10-27Ghrelin is a gut-brain peptide hormone, which binds to the growth hormone secretagogue receptor (GHS-R) to regulate a wide variety of biological processes in fish. Despite these prominent physiological roles, no studies have reported the anatomi[...]texto impreso
Blanco Imperiali, Ayelén M. ; Bertucci, Juan I. ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel ; Unniappan, Suraj | Elsevier | 2016-05The macronutrient composition of diets is a very important factor in the regulation of body weight and metabolism. Several lines of research in mammals have shown that macronutrients differentially regulate metabolic hormones, including ghrelin [...]
