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Autor Lombana, Laura |
Documentos disponibles escritos por este autor (3)
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Tello, Daniel ; Rodríguez-Rodríguez, Mar ; Ortega, Sara ; Lombana, Laura ; Yélamos, Belén ; Gómez-Gutiérrez, Julián ; Peterson, Darrell L. ; Gavilanes, Francisco | Wiley-Blackwell | 2014-06-01We have used an isolated chimeric protein E1340E2661 that includes the ectodomains of the envelope proteins of epatitis C virus to study its interaction with model membranes. E1340E2661 has some of the membrane destabilization properties, vesicl[...]texto impreso
Ortega-Atienza, Sara ; Lombana, Laura ; Gómez-Gutiérrez, Julián ; Yélamos, Belén ; Peterson, Darrell L. ; Gavilanes, Francisco | Academic Press Inc.Elsevier Science | 2014-12Hepatitis C virus (HCV) envelope glycoproteins, E1 and E2, are involved in the first steps of virus infection. The E2 ectodomain can be produced as an isolated form (E2661). However, there is some concern about its proper conformation and the ro[...]texto impreso
Lombana, Laura ; Ortega Atienza, Sara ; Gómez Gutierrez, Julián ; Yélamos, Belén ; Peterson, Darrell ; Gavilanes, Francisco | Elsevier | 2016-03-06We have obtained a chimeric protein containing the ectodomains of hepatitis C virus (HCV) envelope proteins but lacking the region 268-292 of E1. All its structural properties are coincident with those of the corresponding full length chimera. T[...]