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Chioua, Mourad ; Pérez Peña, Javier ; García Font, Nuria ; Moraleda, Ignacio ; Iriepa, Isabel ; Soriano, Elena ; Marco Contelles, José ; Oset Gasque, María Jesús | Future Science | 2015Aim: Due to the complex nature of Alzheimer’s disease, there is a renewed search for multipotent, nonhepatotoxic tacrines. Results: This paper describes the synthesis and in vitro biological evaluation of eight new racemic 3-methyl-4-aryl-2,4,6,[...]texto impreso
Oset Gasque, María Jesús ; González Prieto, María Pilar ; Pérez Peña, Javier ; García Font, Nuria ; Romero Martínez, Alejandro ; Pino Sans, Javier del ; Ramos, Eva ; Hadjipavlou-Litina, Dimitra ; Soriano, Elena ; Chioua, Mourad ; Samadi, Abdelouahid ; Raghuvanshi, Dushyant S. ; Singh, Krishna N. ; Marco Contelles, José | Elsevier | 2014-01-08The pharmacological analysis of racemic chromenotacrines (CT) 1e7, bearing the 11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol ring skeleton, in a series of experiments targeted to explore their potential use for the treatm[...]
