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Ruiz Calvo, Andrea ; Bajo-Grañeras, Raquel ; Maroto, Irene B. ; Zian, Debora ; Grabner, Gernot F. ; García-Taboada, Elena ; Resel, Eva ; Zechner, Rudolf ; Zimmermann, Robert ; Ortega-Gutiérrez, Silvia ; Galve Roperh, Ismael ; Bellocchio, Luigi ; Guzmán, Manuel | Elsevier | 2019-05-15Cannabinoids exert neuroprotection in a wide array of preclinical models. A number of these studies has focused on cannabinoid CB1 receptors in striatal medium spiny neurons (MSNs) and the most characteristic MSN-degenerative disease, Huntington[...]texto impreso
Gamo, Ana M. ; Gónzalez-Vera, Juan A. ; Rueda-Zubiaurre, Ainoa ; Alonso, Dulce ; Vázquez-Villa, Henar ; Martín-Couce, Lidia ; Palomares, Oscar ; López, Juan A. ; Martín-Fontecha, Mar ; Benhamú, Bellinda ; López-Rodríguez, María L. ; Ortega-Gutiérrez, Silvia | Wiley | 2015Determination of the targets of a compound remains an essential aspect in drug discovery. A complete understanding of all binding interactions is critical to recognize in advance both therapeutic effects and undesired consequences. However, the[...]
