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Mela Rivas, Virginia ; Díaz, Francisca ; López Rodríguez, Ana Belén ; Vázquez, María Jesús ; Gertler, Arieh ; Argente, Jesús ; Tena-Sempere, Manuel ; Viveros, María Paz ; Chowen, Julie A. | Oxford University Press | 2015-07Leptin is important in the development of neuroendocrine circuits involved in metabolic control. As both leptin and metabolism influence pubertal development, we hypothesized that early changes in leptin signaling could also modulate hypothalami[...]texto impreso
Cleofé Zapatero, María ; Pérez, Paloma ; Vázquez, María Jesús ; Colmenarejo Sánchez, Gonzalo ; Frailes, Maite de los ; Ramón Olayo, Fernando Antonio | SAGE Publishing | 2015Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine associated with multiple diseases, including neurodegenerative disorders. With the ultimate goal of providing novel chemotypes as starting points for development of disea[...]texto impreso
Mela Rivas, Virginia ; Díaz, Francisca ; Vázquez, María Jesús ; Argente, Jesús ; Tena Sempere, Manuel ; Viveros, María Paz ; Chowen, Julie A. | Cross Mark | 2016Background: Maternal deprivation (MD) during neonatal life can have long-term effects on metabolism and behavior, with males and females responding differently. We previously reported that MD during 24 h at postnatal day (PND) 9 blocks the phys[...]
