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Invasive Candidiasis (IC) poses a major public health problem worldwide. Despite the introduction of new antifungal agents and changes in clinical practices, its morbidity and mortality rates and healthcare costs remain persistently high. This i[...]texto impreso
Vaz, Catarina Oliveira ; Reales Calderón, José Antonio ; Pitarch, Aida ; Vellosillo, Perceval ; Trevisan Herraz, Marco ; Hernáez Sánchez, Maria Luisa ; Monteoliva Díaz, Lucía ; Gil García, Concha | ACS | 2019-04-15Macrophages are involved in the primary human response to Candida albicans. After pathogen recognition, signaling pathways are activated, leading to the production of cytokines, chemokines, and antimicrobial peptides. ATP binding proteins are cr[...]texto impreso
Invasive candidiasis (IC) adds significantly to the morbidity and mortality of non-neutropenic patients if not diagnosed and treated early. To uncover serologic biomarkers that alone or in combination could reliably detect IC in this population,[...]
